Protein kinase C theta is dispensable for suppression mediated by CD25+CD4+ regulatory T cells.
The activation of conventional T cells upon T cell receptor stimulation critically depends on protein kinase C theta (PKCθ). However, its role in regulatory T (Treg) cell function has yet to be fully elucidated. Using siRNA or the potent and PKC family-selective pharmacological inhibitor AEB071, we...
| Váldodahkkit: | , , , , |
|---|---|
| Materiálatiipa: | Artihkal |
| Giella: | English |
| Almmustuhtton: |
Public Library of Science (PLoS)
2017-01-01
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| Ráidu: | PLoS ONE |
| Liŋkkat: | https://doi.org/10.1371/journal.pone.0175463 |