Reactive oxygen species (ROS)-mediated M1 macrophage-dependent nanomedicine remodels inflammatory microenvironment for osteoarthritis recession

Reactive oxygen species (ROS)-mediated M1 macrophage-dependent nanomedicine remodels inflammatory microenvironment for osteoarthritis recession

Osteoarthritis (OA) is a common chronic inflammatory disorder. Effective remodeling of inflammatory microenvironment in the joint is a promising strategy to prevent OA. However, current drugs remain unsatisfactory due to a lack of targeted and effective ways for relieving inflammatory conditions in...

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Bibliographic Details
Main Authors: Chunchun Xue, Jia Tian, Zepeng Cui, Yang Liu, Dawei Sun, Mengting Xiong, Nanxing Yi, Kaiqiang Wang, Xiaofeng Li, Yongjun Wang, Hao Xu, Weian Zhang, Qianqian Liang
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2024-03-01
Series:Bioactive Materials
Subjects:
Reactive oxygen species
Osteoarthritis
Inflammatory microenvironment
Macrophages polarization
Apoptosis
Online Access:http://www.sciencedirect.com/science/article/pii/S2452199X2300347X

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