Epigenetic Regulation Mediated by Methylation in the Pathogenesis and Precision Medicine of Rheumatoid Arthritis

Epigenetic Regulation Mediated by Methylation in the Pathogenesis and Precision Medicine of Rheumatoid Arthritis

Rheumatoid arthritis (RA) is a complex disease triggered by the interaction between genetics and the environment, especially through the shared epitope (SE) and cell surface calreticulin (CSC) theory. However, the available evidence shows that genetic diversity and environmental exposure cannot expl...

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Bibliographic Details
Main Authors: Shicheng Guo, Lingxia Xu, Cen Chang, Runrun Zhang, Yehua Jin, Dongyi He
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-08-01
Series:Frontiers in Genetics
Subjects:
epigenetic
methylation
rheumatoid arthritis
pathogenesis
regulation
Online Access:https://www.frontiersin.org/article/10.3389/fgene.2020.00811/full

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