Ecdysone Receptor-based Singular Gene Switches for Regulated Transgene Expression in Cells and Adult Rodent Tissues

Ecdysone Receptor-based Singular Gene Switches for Regulated Transgene Expression in Cells and Adult Rodent Tissues

Controlled gene expression is an indispensable technique in biomedical research. Here, we report a convenient, straightforward, and reliable way to induce expression of a gene of interest with negligible background expression compared to the most widely used tetracycline (Tet)-regulated system. Expl...

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Bibliographic Details
Main Authors: Seoghyun Lee, Kyung-Cheol Sohn, Dae-Kyoung Choi, Minho Won, Kyeong Ah Park, Sung-Kyu Ju, Kidong Kang, Young-Ki Bae, Gang Min Hur, Hyunju Ro
Format: Article
Language:English
Published: Elsevier 2016-01-01
Series:Molecular Therapy: Nucleic Acids
Subjects:
adenovirus
controlled gene expression
ecdysone receptor (EcR)-based gene regulatory system
tetracycline
tebufenozide
Online Access:http://www.sciencedirect.com/science/article/pii/S2162253117300926

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