Impact of aging and exercise on skeletal muscle mitochondrial capacity, energy metabolism, and physical function
Aging is associated with a progressive loss of muscle function. Here the authors characterize mitochondrial capacity and muscle function in young and older adults with similar habitual physical activity and also compared to older adults with exercise training or with physical impairment.
| Main Authors: | , , , , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2021-08-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-021-24956-2 |
| _version_ | 1818422265857966080 |
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| author | L. Grevendonk N. J. Connell C. McCrum C. E. Fealy L. Bilet Y. M. H. Bruls J. Mevenkamp V. B. Schrauwen-Hinderling J. A. Jörgensen E. Moonen-Kornips G. Schaart B. Havekes J. de Vogel-van den Bosch M. C. E. Bragt K. Meijer P. Schrauwen J. Hoeks |
| author_facet | L. Grevendonk N. J. Connell C. McCrum C. E. Fealy L. Bilet Y. M. H. Bruls J. Mevenkamp V. B. Schrauwen-Hinderling J. A. Jörgensen E. Moonen-Kornips G. Schaart B. Havekes J. de Vogel-van den Bosch M. C. E. Bragt K. Meijer P. Schrauwen J. Hoeks |
| author_sort | L. Grevendonk |
| collection | DOAJ |
| description | Aging is associated with a progressive loss of muscle function. Here the authors characterize mitochondrial capacity and muscle function in young and older adults with similar habitual physical activity and also compared to older adults with exercise training or with physical impairment. |
| first_indexed | 2024-12-14T13:23:31Z |
| format | Article |
| id | doaj.art-035190f53f0041ab9013b063d3712f34 |
| institution | Directory Open Access Journal |
| issn | 2041-1723 |
| language | English |
| last_indexed | 2024-12-14T13:23:31Z |
| publishDate | 2021-08-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Nature Communications |
| spelling | doaj.art-035190f53f0041ab9013b063d3712f342022-12-21T22:59:52ZengNature PortfolioNature Communications2041-17232021-08-0112111710.1038/s41467-021-24956-2Impact of aging and exercise on skeletal muscle mitochondrial capacity, energy metabolism, and physical functionL. Grevendonk0N. J. Connell1C. McCrum2C. E. Fealy3L. Bilet4Y. M. H. Bruls5J. Mevenkamp6V. B. Schrauwen-Hinderling7J. A. Jörgensen8E. Moonen-Kornips9G. Schaart10B. Havekes11J. de Vogel-van den Bosch12M. C. E. Bragt13K. Meijer14P. Schrauwen15J. Hoeks16Department of Nutrition and Movement Sciences, NUTRIM School of Nutrition and Translational Research in Metabolism, Maastricht UniversityDepartment of Nutrition and Movement Sciences, NUTRIM School of Nutrition and Translational Research in Metabolism, Maastricht UniversityDepartment of Nutrition and Movement Sciences, NUTRIM School of Nutrition and Translational Research in Metabolism, Maastricht UniversityDepartment of Nutrition and Movement Sciences, NUTRIM School of Nutrition and Translational Research in Metabolism, Maastricht UniversityDepartment of Nutrition and Movement Sciences, NUTRIM School of Nutrition and Translational Research in Metabolism, Maastricht UniversityDepartment of Radiology and Nuclear Medicine, NUTRIM School of Nutrition and Translational Research in Metabolism, Maastricht University Medical Center+Department of Radiology and Nuclear Medicine, NUTRIM School of Nutrition and Translational Research in Metabolism, Maastricht University Medical Center+Department of Nutrition and Movement Sciences, NUTRIM School of Nutrition and Translational Research in Metabolism, Maastricht UniversityDepartment of Nutrition and Movement Sciences, NUTRIM School of Nutrition and Translational Research in Metabolism, Maastricht UniversityDepartment of Nutrition and Movement Sciences, NUTRIM School of Nutrition and Translational Research in Metabolism, Maastricht UniversityDepartment of Nutrition and Movement Sciences, NUTRIM School of Nutrition and Translational Research in Metabolism, Maastricht UniversityDepartment of Nutrition and Movement Sciences, NUTRIM School of Nutrition and Translational Research in Metabolism, Maastricht UniversityDanone Nutricia ResearchFriesland-CampinaDepartment of Nutrition and Movement Sciences, NUTRIM School of Nutrition and Translational Research in Metabolism, Maastricht UniversityDepartment of Nutrition and Movement Sciences, NUTRIM School of Nutrition and Translational Research in Metabolism, Maastricht UniversityDepartment of Nutrition and Movement Sciences, NUTRIM School of Nutrition and Translational Research in Metabolism, Maastricht UniversityAging is associated with a progressive loss of muscle function. Here the authors characterize mitochondrial capacity and muscle function in young and older adults with similar habitual physical activity and also compared to older adults with exercise training or with physical impairment.https://doi.org/10.1038/s41467-021-24956-2 |
| spellingShingle | L. Grevendonk N. J. Connell C. McCrum C. E. Fealy L. Bilet Y. M. H. Bruls J. Mevenkamp V. B. Schrauwen-Hinderling J. A. Jörgensen E. Moonen-Kornips G. Schaart B. Havekes J. de Vogel-van den Bosch M. C. E. Bragt K. Meijer P. Schrauwen J. Hoeks Impact of aging and exercise on skeletal muscle mitochondrial capacity, energy metabolism, and physical function Nature Communications |
| title | Impact of aging and exercise on skeletal muscle mitochondrial capacity, energy metabolism, and physical function |
| title_full | Impact of aging and exercise on skeletal muscle mitochondrial capacity, energy metabolism, and physical function |
| title_fullStr | Impact of aging and exercise on skeletal muscle mitochondrial capacity, energy metabolism, and physical function |
| title_full_unstemmed | Impact of aging and exercise on skeletal muscle mitochondrial capacity, energy metabolism, and physical function |
| title_short | Impact of aging and exercise on skeletal muscle mitochondrial capacity, energy metabolism, and physical function |
| title_sort | impact of aging and exercise on skeletal muscle mitochondrial capacity energy metabolism and physical function |
| url | https://doi.org/10.1038/s41467-021-24956-2 |
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