Effects of Insufficient Levels of Dietary Protein on IGF-I and IGFBPs in Young Chickens
The influence of varying dietary proteins levels from 0% to 18%, which is the level of dietary protein requirement, on plasma IGF-I concentration and tissue IGFBP-2 and -4 gene expression was examined. Body weight gain was gradually lowered by decreasing dietary protein levels from 18% to 4.5%, and...
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| Format: | Article |
| Language: | English |
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Japan Poultry Science Association
2010-07-01
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| Series: | The Journal of Poultry Science |
| Subjects: | |
| Online Access: | https://www.jstage.jst.go.jp/article/jpsa/47/3/47_010031/_pdf/-char/en |
| _version_ | 1827937993781936128 |
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| author | Kenji Nagao Kohzy Hiramatsu Akira Tsukada Kazumi Kita |
| author_facet | Kenji Nagao Kohzy Hiramatsu Akira Tsukada Kazumi Kita |
| author_sort | Kenji Nagao |
| collection | DOAJ |
| description | The influence of varying dietary proteins levels from 0% to 18%, which is the level of dietary protein requirement, on plasma IGF-I concentration and tissue IGFBP-2 and -4 gene expression was examined. Body weight gain was gradually lowered by decreasing dietary protein levels from 18% to 4.5%, and body weight was lost when chickens fed a protein-free diet. Plasma IGF-I concentration of chickens fed the 18% crude protein diet was the highest of all, and it was gradually decreased by reducing dietary protein concentrations. Gene expression of IGFBP-2 in the gizzard was elevated by decreasing dietary protein levels from 18% to 9%, and the further reduction in dietary protein content lowered gizzard IGFBP-2 gene expression. No significant change in hepatic IGFBP-4 gene expression was observed in chickens fed experimental diets with varying dietary protein levels. Multiple linear regression analysis revealed that the influence of the change in plasma IGF-I concentration and gizzard IGFBP-2 gene expression on body weight change of chickens fed varying amounts of dietary protein seemed to be independent because the interactive effect of both factors on body weight change was not significant. |
| first_indexed | 2024-03-13T08:33:29Z |
| format | Article |
| id | doaj.art-03569e7a1bf54e12b8df0b31c435adad |
| institution | Directory Open Access Journal |
| issn | 1346-7395 1349-0486 |
| language | English |
| last_indexed | 2024-03-13T08:33:29Z |
| publishDate | 2010-07-01 |
| publisher | Japan Poultry Science Association |
| record_format | Article |
| series | The Journal of Poultry Science |
| spelling | doaj.art-03569e7a1bf54e12b8df0b31c435adad2023-05-31T00:55:35ZengJapan Poultry Science AssociationThe Journal of Poultry Science1346-73951349-04862010-07-0147323623910.2141/jpsa.010031jpsaEffects of Insufficient Levels of Dietary Protein on IGF-I and IGFBPs in Young ChickensKenji Nagao0Kohzy Hiramatsu1Akira Tsukada2Kazumi Kita3University Farm, Graduate School of Bioagricultural Sciences, Nagoya University, JapanFaculty of Agriculture, Shinshu University, JapanGraduate School of Bioagricultural Sciences, Nagoya University, JapanFaculty of Agriculture, Iwate University, JapanThe influence of varying dietary proteins levels from 0% to 18%, which is the level of dietary protein requirement, on plasma IGF-I concentration and tissue IGFBP-2 and -4 gene expression was examined. Body weight gain was gradually lowered by decreasing dietary protein levels from 18% to 4.5%, and body weight was lost when chickens fed a protein-free diet. Plasma IGF-I concentration of chickens fed the 18% crude protein diet was the highest of all, and it was gradually decreased by reducing dietary protein concentrations. Gene expression of IGFBP-2 in the gizzard was elevated by decreasing dietary protein levels from 18% to 9%, and the further reduction in dietary protein content lowered gizzard IGFBP-2 gene expression. No significant change in hepatic IGFBP-4 gene expression was observed in chickens fed experimental diets with varying dietary protein levels. Multiple linear regression analysis revealed that the influence of the change in plasma IGF-I concentration and gizzard IGFBP-2 gene expression on body weight change of chickens fed varying amounts of dietary protein seemed to be independent because the interactive effect of both factors on body weight change was not significant.https://www.jstage.jst.go.jp/article/jpsa/47/3/47_010031/_pdf/-char/endietary proteinigf-iigfbp-2igfbp-4 |
| spellingShingle | Kenji Nagao Kohzy Hiramatsu Akira Tsukada Kazumi Kita Effects of Insufficient Levels of Dietary Protein on IGF-I and IGFBPs in Young Chickens The Journal of Poultry Science dietary protein igf-i igfbp-2 igfbp-4 |
| title | Effects of Insufficient Levels of Dietary Protein on IGF-I and IGFBPs in Young Chickens |
| title_full | Effects of Insufficient Levels of Dietary Protein on IGF-I and IGFBPs in Young Chickens |
| title_fullStr | Effects of Insufficient Levels of Dietary Protein on IGF-I and IGFBPs in Young Chickens |
| title_full_unstemmed | Effects of Insufficient Levels of Dietary Protein on IGF-I and IGFBPs in Young Chickens |
| title_short | Effects of Insufficient Levels of Dietary Protein on IGF-I and IGFBPs in Young Chickens |
| title_sort | effects of insufficient levels of dietary protein on igf i and igfbps in young chickens |
| topic | dietary protein igf-i igfbp-2 igfbp-4 |
| url | https://www.jstage.jst.go.jp/article/jpsa/47/3/47_010031/_pdf/-char/en |
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