Safety and efficacy of sirolimus combined with endocrine therapy in patients with advanced hormone receptor-positive breast cancer and the exploration of biomarkers

Background: We performed a retrospective study on the efficacy and safety of sirolimus (an mTOR inhibitor) in hormone receptor (HR)-positive advanced breast cancer and searched for biomarkers to predict its efficacy. Methods: All patients with HR-positive metastatic breast cancer treated with siroli...

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Bibliographic Details
Main Authors: Zongbi Yi, Binliang Liu, Xiaoying Sun, Guohua Rong, Wenna Wang, Hui Li, Xiuwen Guan, Lixi Li, Jingtong Zhai, Chunxiao Li, Haili Qian, Fei Ma, Binghe Xu
Format: Article
Language:English
Published: Elsevier 2020-08-01
Series:Breast
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0960977620300916