Prevalence and risk factors for Toxoplasma gondii infection among pregnant and postpartum women attended at public healthcare facilities in the City of Niterói, State of Rio de Janeiro, Brazil
Introduction To determine the prevalence of immunoglobulin G (IgG) and immunoglobulin M (IgM) anti-Toxoplasma gondii antibodies among pregnant and postpartum women attended within the public healthcare system in Niterói, State of Rio de Janeiro, and to detect possible exposure factors associate...
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| Format: | Article |
| Language: | English |
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Sociedade Brasileira de Medicina Tropical (SBMT)
2013-04-01
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| Series: | Revista da Sociedade Brasileira de Medicina Tropical |
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| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822013000200200&lng=en&tlng=en |
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| author | Fernanda Loureiro de Moura Maria Regina Reis Amendoeira Otílio Machado Pereira Bastos Danuza Pinheiro Bastos Garcia de Mattos Ana Beatriz Monteiro Fonseca José Leonardo Nicolau Leandro Baptista das Neves Patricia Riddell Millar |
| author_facet | Fernanda Loureiro de Moura Maria Regina Reis Amendoeira Otílio Machado Pereira Bastos Danuza Pinheiro Bastos Garcia de Mattos Ana Beatriz Monteiro Fonseca José Leonardo Nicolau Leandro Baptista das Neves Patricia Riddell Millar |
| author_sort | Fernanda Loureiro de Moura |
| collection | DOAJ |
| description | Introduction To determine the prevalence of immunoglobulin G (IgG) and immunoglobulin M (IgM) anti-Toxoplasma gondii antibodies among pregnant and postpartum women attended within the public healthcare system in Niterói, State of Rio de Janeiro, and to detect possible exposure factors associated with T. gondii infection in this population. Methods IgM and IgG anti-T. gondii antibodies were investigated in 276 pregnant and 124 postpartum women by using the indirect immunofluorescence (IFAT) and immunoenzymatic assay (ELISA) techniques. The participants were selected by convenience sampling. All these 400 patients filled out a free and informed consent statement, answered an epidemiological questionnaire and were informed about the disease. Results Among the 400 samples analyzed, 234 (58.5%) were reactive to IgG anti-T. gondii antibodies, according to the IFAT and/or ELISA assay. One pregnant woman was found to be reactive to IgM anti-T. gondii antibodies, with an intermediate IgG avidity test. Risk factor analysis showed that seropositivity was significantly associated (p<0.05) with age, contact with cats and presence of rodents at home. Through a logistic regression model, these associations were confirmed for age and contact with cats, while education at least of the high school level was found to be a protective factor. Conclusions The prevalence rate of IgG anti-T. gondii antibodies in the City of Niterói was high and the risk factors for infection detected after multivariate analysis were: age over 30 years, contact with cats and education levels lower than university graduate level. |
| first_indexed | 2024-04-12T14:48:32Z |
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| id | doaj.art-035fc577151244baa4d2e3a5f655ecff |
| institution | Directory Open Access Journal |
| issn | 1678-9849 |
| language | English |
| last_indexed | 2024-04-12T14:48:32Z |
| publishDate | 2013-04-01 |
| publisher | Sociedade Brasileira de Medicina Tropical (SBMT) |
| record_format | Article |
| series | Revista da Sociedade Brasileira de Medicina Tropical |
| spelling | doaj.art-035fc577151244baa4d2e3a5f655ecff2022-12-22T03:28:34ZengSociedade Brasileira de Medicina Tropical (SBMT)Revista da Sociedade Brasileira de Medicina Tropical1678-98492013-04-0146220020710.1590/0037-8682-1613-2013S0037-86822013000200200Prevalence and risk factors for Toxoplasma gondii infection among pregnant and postpartum women attended at public healthcare facilities in the City of Niterói, State of Rio de Janeiro, BrazilFernanda Loureiro de MouraMaria Regina Reis AmendoeiraOtílio Machado Pereira BastosDanuza Pinheiro Bastos Garcia de MattosAna Beatriz Monteiro FonsecaJosé Leonardo NicolauLeandro Baptista das NevesPatricia Riddell MillarIntroduction To determine the prevalence of immunoglobulin G (IgG) and immunoglobulin M (IgM) anti-Toxoplasma gondii antibodies among pregnant and postpartum women attended within the public healthcare system in Niterói, State of Rio de Janeiro, and to detect possible exposure factors associated with T. gondii infection in this population. Methods IgM and IgG anti-T. gondii antibodies were investigated in 276 pregnant and 124 postpartum women by using the indirect immunofluorescence (IFAT) and immunoenzymatic assay (ELISA) techniques. The participants were selected by convenience sampling. All these 400 patients filled out a free and informed consent statement, answered an epidemiological questionnaire and were informed about the disease. Results Among the 400 samples analyzed, 234 (58.5%) were reactive to IgG anti-T. gondii antibodies, according to the IFAT and/or ELISA assay. One pregnant woman was found to be reactive to IgM anti-T. gondii antibodies, with an intermediate IgG avidity test. Risk factor analysis showed that seropositivity was significantly associated (p<0.05) with age, contact with cats and presence of rodents at home. Through a logistic regression model, these associations were confirmed for age and contact with cats, while education at least of the high school level was found to be a protective factor. Conclusions The prevalence rate of IgG anti-T. gondii antibodies in the City of Niterói was high and the risk factors for infection detected after multivariate analysis were: age over 30 years, contact with cats and education levels lower than university graduate level.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822013000200200&lng=en&tlng=enToxoplasma gondiiPregnant womenPostpartum womenSeroprevalence |
| spellingShingle | Fernanda Loureiro de Moura Maria Regina Reis Amendoeira Otílio Machado Pereira Bastos Danuza Pinheiro Bastos Garcia de Mattos Ana Beatriz Monteiro Fonseca José Leonardo Nicolau Leandro Baptista das Neves Patricia Riddell Millar Prevalence and risk factors for Toxoplasma gondii infection among pregnant and postpartum women attended at public healthcare facilities in the City of Niterói, State of Rio de Janeiro, Brazil Revista da Sociedade Brasileira de Medicina Tropical Toxoplasma gondii Pregnant women Postpartum women Seroprevalence |
| title | Prevalence and risk factors for Toxoplasma gondii infection among pregnant and postpartum women attended at public healthcare facilities in the City of Niterói, State of Rio de Janeiro, Brazil |
| title_full | Prevalence and risk factors for Toxoplasma gondii infection among pregnant and postpartum women attended at public healthcare facilities in the City of Niterói, State of Rio de Janeiro, Brazil |
| title_fullStr | Prevalence and risk factors for Toxoplasma gondii infection among pregnant and postpartum women attended at public healthcare facilities in the City of Niterói, State of Rio de Janeiro, Brazil |
| title_full_unstemmed | Prevalence and risk factors for Toxoplasma gondii infection among pregnant and postpartum women attended at public healthcare facilities in the City of Niterói, State of Rio de Janeiro, Brazil |
| title_short | Prevalence and risk factors for Toxoplasma gondii infection among pregnant and postpartum women attended at public healthcare facilities in the City of Niterói, State of Rio de Janeiro, Brazil |
| title_sort | prevalence and risk factors for toxoplasma gondii infection among pregnant and postpartum women attended at public healthcare facilities in the city of niteroi state of rio de janeiro brazil |
| topic | Toxoplasma gondii Pregnant women Postpartum women Seroprevalence |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822013000200200&lng=en&tlng=en |
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