Rapid Radiological Worsening and Cytokine Storm Syndrome in COVID-19 Pneumonia

Background: In June 2020, a large randomised controlled clinical trial in the UK found that dexamethasone was effective in reducing the number of deaths in patients with severe coronavirus disease 2019 (COVID-19). Case description: We describe a patient with rapid worsening of COVID-19 pneumonia a...

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Main Authors: Yvon Ruch, Charlotte Kaeuffer, Aurélien Guffroy, Nicolas Lefebvre, Yves Hansmann, François Danion
Format: Article
Language:English
Published: SMC MEDIA SRL 2020-07-01
Series:European Journal of Case Reports in Internal Medicine
Subjects:
Online Access:https://www.ejcrim.com/index.php/EJCRIM/article/view/1822
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author Yvon Ruch
Charlotte Kaeuffer
Aurélien Guffroy
Nicolas Lefebvre
Yves Hansmann
François Danion
author_facet Yvon Ruch
Charlotte Kaeuffer
Aurélien Guffroy
Nicolas Lefebvre
Yves Hansmann
François Danion
author_sort Yvon Ruch
collection DOAJ
description Background: In June 2020, a large randomised controlled clinical trial in the UK found that dexamethasone was effective in reducing the number of deaths in patients with severe coronavirus disease 2019 (COVID-19). Case description: We describe a patient with rapid worsening of COVID-19 pneumonia and its dramatic improvement under corticosteroids. Discussion: Corticosteroids could be useful in patients with an inflammatory profile, considering that acute respiratory distress syndrome may be the consequence of cytokine storm syndrome.
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spelling doaj.art-0362681fd8224f19b35177598eb648ea2022-12-22T03:04:45ZengSMC MEDIA SRLEuropean Journal of Case Reports in Internal Medicine2284-25942020-07-0110.12890/2020_0018221449Rapid Radiological Worsening and Cytokine Storm Syndrome in COVID-19 PneumoniaYvon Ruch0Charlotte Kaeuffer1Aurélien Guffroy2Nicolas Lefebvre3Yves Hansmann4François Danion5Department of Infectious Diseases, Strasbourg University Hospital, Strasbourg, FranceDepartment of Infectious Diseases, Strasbourg University Hospital, Strasbourg, FranceDepartment of Clinical Immunology and Internal Medicine, Strasbourg University Hospital, Strasbourg, FranceDepartment of Infectious Diseases, Strasbourg University Hospital, Strasbourg, FranceDepartment of Infectious Diseases, Strasbourg University Hospital, Strasbourg, FranceDepartment of Infectious Diseases, Strasbourg University Hospital, Strasbourg, FranceBackground: In June 2020, a large randomised controlled clinical trial in the UK found that dexamethasone was effective in reducing the number of deaths in patients with severe coronavirus disease 2019 (COVID-19). Case description: We describe a patient with rapid worsening of COVID-19 pneumonia and its dramatic improvement under corticosteroids. Discussion: Corticosteroids could be useful in patients with an inflammatory profile, considering that acute respiratory distress syndrome may be the consequence of cytokine storm syndrome.https://www.ejcrim.com/index.php/EJCRIM/article/view/1822covid-19coronaviruscytokine storm syndromecomputed tomographycorticosteroids
spellingShingle Yvon Ruch
Charlotte Kaeuffer
Aurélien Guffroy
Nicolas Lefebvre
Yves Hansmann
François Danion
Rapid Radiological Worsening and Cytokine Storm Syndrome in COVID-19 Pneumonia
European Journal of Case Reports in Internal Medicine
covid-19
coronavirus
cytokine storm syndrome
computed tomography
corticosteroids
title Rapid Radiological Worsening and Cytokine Storm Syndrome in COVID-19 Pneumonia
title_full Rapid Radiological Worsening and Cytokine Storm Syndrome in COVID-19 Pneumonia
title_fullStr Rapid Radiological Worsening and Cytokine Storm Syndrome in COVID-19 Pneumonia
title_full_unstemmed Rapid Radiological Worsening and Cytokine Storm Syndrome in COVID-19 Pneumonia
title_short Rapid Radiological Worsening and Cytokine Storm Syndrome in COVID-19 Pneumonia
title_sort rapid radiological worsening and cytokine storm syndrome in covid 19 pneumonia
topic covid-19
coronavirus
cytokine storm syndrome
computed tomography
corticosteroids
url https://www.ejcrim.com/index.php/EJCRIM/article/view/1822
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AT aurelienguffroy rapidradiologicalworseningandcytokinestormsyndromeincovid19pneumonia
AT nicolaslefebvre rapidradiologicalworseningandcytokinestormsyndromeincovid19pneumonia
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