ESBL‐production in Escherichia coli and Klebsiella pneumoniae isolates from Nigeria
Abstract The worldwide increase in infections caused by extended‐spectrum beta‐lactamase‐ (ESBL) and AmpC‐producing Enterobacteriaceae (ESBL‐E) is a concern. Surveillance is extensive in Europe, North America, and Asia. Yet, there is no summarizing surveillance in Africa. This study aimed to perform...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2019-09-01
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| Series: | MicrobiologyOpen |
| Subjects: | |
| Online Access: | https://doi.org/10.1002/mbo3.816 |
| _version_ | 1828789747813711872 |
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| author | Frederik B. Hertz Fillip Jansåker Kenneth O. Okon Ibrahim S. Abdulmumin Joseph O. Onah Joshua Ladan Jenny D. Knudsen |
| author_facet | Frederik B. Hertz Fillip Jansåker Kenneth O. Okon Ibrahim S. Abdulmumin Joseph O. Onah Joshua Ladan Jenny D. Knudsen |
| author_sort | Frederik B. Hertz |
| collection | DOAJ |
| description | Abstract The worldwide increase in infections caused by extended‐spectrum beta‐lactamase‐ (ESBL) and AmpC‐producing Enterobacteriaceae (ESBL‐E) is a concern. Surveillance is extensive in Europe, North America, and Asia. Yet, there is no summarizing surveillance in Africa. This study aimed to perform a preliminary investigation on the prevalence of ESBL‐E in the northeastern part of Nigeria. However, of the 60 samples collected, we were able to culture 15 Escherichia coli and 7 Klebsiella spp. only. In the collection of clinical hospital samples, we found eight of 15 E. coli isolates to be ESBL (53%) and two out of seven Klebsiella spp. to be ESBL/AmpC (29%). Due to the limitations of this study, our findings cannot take a broad view on the prevalence of ESBL‐E, in Nigeria and other parts of Africa. Yet, to know which genes encode ESBL in Nigeria, and to know exact prevalence of every ESBL gene would be of importance. |
| first_indexed | 2024-12-12T01:17:05Z |
| format | Article |
| id | doaj.art-037091034ca44c37b9d362288673dce7 |
| institution | Directory Open Access Journal |
| issn | 2045-8827 |
| language | English |
| last_indexed | 2024-12-12T01:17:05Z |
| publishDate | 2019-09-01 |
| publisher | Wiley |
| record_format | Article |
| series | MicrobiologyOpen |
| spelling | doaj.art-037091034ca44c37b9d362288673dce72022-12-22T00:43:18ZengWileyMicrobiologyOpen2045-88272019-09-0189n/an/a10.1002/mbo3.816ESBL‐production in Escherichia coli and Klebsiella pneumoniae isolates from NigeriaFrederik B. Hertz0Fillip Jansåker1Kenneth O. Okon2Ibrahim S. Abdulmumin3Joseph O. Onah4Joshua Ladan5Jenny D. Knudsen6Department of Clinical Microbiology, Hvidovre Hospital University of Copenhagen Hvidovre DenmarkDepartment of Clinical Microbiology, Hvidovre Hospital University of Copenhagen Hvidovre DenmarkDepartment of Medical Microbiology, Federal Medical Centre Makurdi NigeriaDepartment of Medical Microbiology Abubakar Tafawa Balewa University Teaching Hospital BauchiClinton Health Access Initiative Abuja NigeriaDepartment of Disease and Immunization National Primary Health Care Development Agency Abuja NigeriaDepartment of Clinical Microbiology, Hvidovre Hospital University of Copenhagen Hvidovre DenmarkAbstract The worldwide increase in infections caused by extended‐spectrum beta‐lactamase‐ (ESBL) and AmpC‐producing Enterobacteriaceae (ESBL‐E) is a concern. Surveillance is extensive in Europe, North America, and Asia. Yet, there is no summarizing surveillance in Africa. This study aimed to perform a preliminary investigation on the prevalence of ESBL‐E in the northeastern part of Nigeria. However, of the 60 samples collected, we were able to culture 15 Escherichia coli and 7 Klebsiella spp. only. In the collection of clinical hospital samples, we found eight of 15 E. coli isolates to be ESBL (53%) and two out of seven Klebsiella spp. to be ESBL/AmpC (29%). Due to the limitations of this study, our findings cannot take a broad view on the prevalence of ESBL‐E, in Nigeria and other parts of Africa. Yet, to know which genes encode ESBL in Nigeria, and to know exact prevalence of every ESBL gene would be of importance.https://doi.org/10.1002/mbo3.816EnterobacteriaceaeESBLEscherichia coliKlebsiella pneumoniaeNigeria |
| spellingShingle | Frederik B. Hertz Fillip Jansåker Kenneth O. Okon Ibrahim S. Abdulmumin Joseph O. Onah Joshua Ladan Jenny D. Knudsen ESBL‐production in Escherichia coli and Klebsiella pneumoniae isolates from Nigeria MicrobiologyOpen Enterobacteriaceae ESBL Escherichia coli Klebsiella pneumoniae Nigeria |
| title | ESBL‐production in Escherichia coli and Klebsiella pneumoniae isolates from Nigeria |
| title_full | ESBL‐production in Escherichia coli and Klebsiella pneumoniae isolates from Nigeria |
| title_fullStr | ESBL‐production in Escherichia coli and Klebsiella pneumoniae isolates from Nigeria |
| title_full_unstemmed | ESBL‐production in Escherichia coli and Klebsiella pneumoniae isolates from Nigeria |
| title_short | ESBL‐production in Escherichia coli and Klebsiella pneumoniae isolates from Nigeria |
| title_sort | esbl production in escherichia coli and klebsiella pneumoniae isolates from nigeria |
| topic | Enterobacteriaceae ESBL Escherichia coli Klebsiella pneumoniae Nigeria |
| url | https://doi.org/10.1002/mbo3.816 |
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