Targeting SR-BI for cancer diagnostics, imaging and therapy

Targeting SR-BI for cancer diagnostics, imaging and therapy

Scavenger receptor class B type I (SR-BI) plays an important role in trafficking cholesteryl esters between the core of high density lipoprotein and the liver. Interestingly, this integral membrane protein receptor is also implicated in the metabolism of cholesterol by cancer cells, whereby overexpr...

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Bibliographic Details
Main Authors: Maneesha Amrita Rajora, Gang Zheng
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-09-01
Series:Frontiers in Pharmacology
Subjects:
Scavenger Receptors, Class B
HDL
cancer therapy
Cancer biomarkers
cancer imaging
theranostics
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphar.2016.00326/full

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