Increasing dietary oat fibre decreases the permeability of intestinal mucus
This study investigates the influence of the dietary fibre β-glucan on nutrient composition and mucus permeability.Pigs were fed a standard diet or a diet containing twice the β-glucan content for 3 days (n = 5 per group), followed by the collection of small intestinal mucus and tissue samples. Samp...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2016-10-01
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| Series: | Journal of Functional Foods |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1756464616302286 |
| _version_ | 1819320502288646144 |
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| author | Alan Mackie Neil Rigby Pascale Harvey Balazs Bajka |
| author_facet | Alan Mackie Neil Rigby Pascale Harvey Balazs Bajka |
| author_sort | Alan Mackie |
| collection | DOAJ |
| description | This study investigates the influence of the dietary fibre β-glucan on nutrient composition and mucus permeability.Pigs were fed a standard diet or a diet containing twice the β-glucan content for 3 days (n = 5 per group), followed by the collection of small intestinal mucus and tissue samples. Samples of the consumed diets were subjected to in vitro digestion to determine β-glucan release, nutrient profile and assessment of mucus permeability.In vitro digestion of the diets indicated that 90% of the β-glucan was released in the proximal small intestine. Measurements of intestinal mucus showed a reduction in permeability to 100 nm latex beads and also lipid from the digested enhanced β-glucan diet.The data from this study show for the first time that reducing mass transfer of bile and lipid through the intestinal mucus layer may be one way in which this decrease in bile reabsorption by soluble fibre is enabled. |
| first_indexed | 2024-12-24T11:20:36Z |
| format | Article |
| id | doaj.art-0371bd93326a4bdd8685f8a16a67ac40 |
| institution | Directory Open Access Journal |
| issn | 1756-4646 |
| language | English |
| last_indexed | 2024-12-24T11:20:36Z |
| publishDate | 2016-10-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Journal of Functional Foods |
| spelling | doaj.art-0371bd93326a4bdd8685f8a16a67ac402022-12-21T16:58:16ZengElsevierJournal of Functional Foods1756-46462016-10-0126418427Increasing dietary oat fibre decreases the permeability of intestinal mucusAlan Mackie0Neil Rigby1Pascale Harvey2Balazs Bajka3School of Food Science and Nutrition, University of Leeds, Leeds LS29JT, UK; Corresponding author. Institute of Food Research, Norwich Research Park, Colney Lane, Norwich NR4 7UA, UK. Fax: +44 (0)113 343 2982.Institute of Food Research, Norwich Research Park, Colney Lane, Norwich NR4 7UA, UKEaston Otley College, Easton, Norwich NR9 5DX, UKInstitute of Food Research, Norwich Research Park, Colney Lane, Norwich NR4 7UA, UKThis study investigates the influence of the dietary fibre β-glucan on nutrient composition and mucus permeability.Pigs were fed a standard diet or a diet containing twice the β-glucan content for 3 days (n = 5 per group), followed by the collection of small intestinal mucus and tissue samples. Samples of the consumed diets were subjected to in vitro digestion to determine β-glucan release, nutrient profile and assessment of mucus permeability.In vitro digestion of the diets indicated that 90% of the β-glucan was released in the proximal small intestine. Measurements of intestinal mucus showed a reduction in permeability to 100 nm latex beads and also lipid from the digested enhanced β-glucan diet.The data from this study show for the first time that reducing mass transfer of bile and lipid through the intestinal mucus layer may be one way in which this decrease in bile reabsorption by soluble fibre is enabled.http://www.sciencedirect.com/science/article/pii/S1756464616302286Dietary fibreBeta-glucanPorcineMucusPermeabilityDiffusion |
| spellingShingle | Alan Mackie Neil Rigby Pascale Harvey Balazs Bajka Increasing dietary oat fibre decreases the permeability of intestinal mucus Journal of Functional Foods Dietary fibre Beta-glucan Porcine Mucus Permeability Diffusion |
| title | Increasing dietary oat fibre decreases the permeability of intestinal mucus |
| title_full | Increasing dietary oat fibre decreases the permeability of intestinal mucus |
| title_fullStr | Increasing dietary oat fibre decreases the permeability of intestinal mucus |
| title_full_unstemmed | Increasing dietary oat fibre decreases the permeability of intestinal mucus |
| title_short | Increasing dietary oat fibre decreases the permeability of intestinal mucus |
| title_sort | increasing dietary oat fibre decreases the permeability of intestinal mucus |
| topic | Dietary fibre Beta-glucan Porcine Mucus Permeability Diffusion |
| url | http://www.sciencedirect.com/science/article/pii/S1756464616302286 |
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