The TOR Signaling Pathway in Spatial and Temporal Control of Cell Size and Growth

The TOR Signaling Pathway in Spatial and Temporal Control of Cell Size and Growth

Cell size is amenable by genetic and environmental factors. The highly conserved nutrient-responsive Target of Rapamycin (TOR) signaling pathway regulates cellular metabolic status and growth in response to numerous inputs. Timing and duration of TOR pathway activity is pivotal for both cell mass bu...

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Bibliographic Details
Main Authors: Suam Gonzalez, Charalampos Rallis
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-06-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
cell size
cell cycle
growth
rapamycin
signaling
nutrients
Online Access:http://journal.frontiersin.org/article/10.3389/fcell.2017.00061/full

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