Foreign Nationality, Family Psychiatry History and Pregestational Neoplastic Disease as Predictors of Perinatal Depression in a Cohort of Healthy Pregnant and Puerperal Women during the COVID-19 Pandemic
<b>Background:</b> Perinatal depression (PND) represents one of the most common mental disorders in the pregnancy and/or postpartum period, with a 5–25% prevalence rate. Our aim was to investigate predictors associated with PND in a cohort of pregnant and puerperal women based in an Ital...
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| Format: | Article |
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MDPI AG
2023-02-01
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| Series: | Healthcare |
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| Online Access: | https://www.mdpi.com/2227-9032/11/3/428 |
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| author | Laura Orsolini Simone Pompili Antonella Mauro Umberto Volpe |
| author_facet | Laura Orsolini Simone Pompili Antonella Mauro Umberto Volpe |
| author_sort | Laura Orsolini |
| collection | DOAJ |
| description | <b>Background:</b> Perinatal depression (PND) represents one of the most common mental disorders in the pregnancy and/or postpartum period, with a 5–25% prevalence rate. Our aim was to investigate predictors associated with PND in a cohort of pregnant and puerperal women based in an Italian setting during the COVID-19 pandemic. <b>Methods:</b> We retrospectively recruited 199 (55 pregnant and 144 puerperal) women, afferent to our Perinatal Mental Outpatient Service of Ancona (Italy). Participants were administered an ad hoc case-report form, Whooley Questions (WQ), the General Health Questionnaire-12 (GHQ-12), the Stress Holmes-Rahe scale (HR) and the Edinburgh Postnatal Depression Scale (EPDS). <b>Results:</b> Around 10% of the sample had a confirmed PND. Being a foreigner woman (RR = 3.8), having a positive psychiatric family history (RR = 5.3), a pre-pregnancy medical comorbidity (RR = 1.85) and a comorbid medical illness occurring during the pregnancy (RR = 2) were much likely associated with PND. Multiple linear regression analysis demonstrated that GHQ, medium- and high-risk at the HR, foreign nationality, positive family psychiatric history, and neoplastic disease before conception significantly predicted EPDS [<i>F</i>(1, 197) = 10.086, <i>R</i><sup>2</sup> = 0.324, <i>p</i> < 0.001]. <b>Limitations:</b> The sample size, poor heterogeneity in terms of socio-demographic, clinical and gynecological-obstetric characteristics, the cross-sectional design of the study. <b>Conclusions:</b> Our study showed a set of predictors associated with a higher risk for the PND onset, including gestational and pregestational medical disease. Our findings outline the need to screen all fertile women, particularly in gynecological and medical settings, in order to identify at-risk women for PND and promptly suggest a psychiatric consultation. |
| first_indexed | 2024-03-11T09:43:25Z |
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| institution | Directory Open Access Journal |
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| language | English |
| last_indexed | 2024-03-11T09:43:25Z |
| publishDate | 2023-02-01 |
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| record_format | Article |
| series | Healthcare |
| spelling | doaj.art-0376689a038840c6aa03085241a21bb32023-11-16T16:45:13ZengMDPI AGHealthcare2227-90322023-02-0111342810.3390/healthcare11030428Foreign Nationality, Family Psychiatry History and Pregestational Neoplastic Disease as Predictors of Perinatal Depression in a Cohort of Healthy Pregnant and Puerperal Women during the COVID-19 PandemicLaura Orsolini0Simone Pompili1Antonella Mauro2Umberto Volpe3Unit of Clinical Psychiatry, Department of Neurosciences/DIMSC, Polytechnic University of Marche, 60126 Ancona, ItalyUnit of Clinical Psychiatry, Department of Neurosciences/DIMSC, Polytechnic University of Marche, 60126 Ancona, ItalyUnit of Clinical Psychiatry, Department of Neurosciences/DIMSC, Polytechnic University of Marche, 60126 Ancona, ItalyUnit of Clinical Psychiatry, Department of Neurosciences/DIMSC, Polytechnic University of Marche, 60126 Ancona, Italy<b>Background:</b> Perinatal depression (PND) represents one of the most common mental disorders in the pregnancy and/or postpartum period, with a 5–25% prevalence rate. Our aim was to investigate predictors associated with PND in a cohort of pregnant and puerperal women based in an Italian setting during the COVID-19 pandemic. <b>Methods:</b> We retrospectively recruited 199 (55 pregnant and 144 puerperal) women, afferent to our Perinatal Mental Outpatient Service of Ancona (Italy). Participants were administered an ad hoc case-report form, Whooley Questions (WQ), the General Health Questionnaire-12 (GHQ-12), the Stress Holmes-Rahe scale (HR) and the Edinburgh Postnatal Depression Scale (EPDS). <b>Results:</b> Around 10% of the sample had a confirmed PND. Being a foreigner woman (RR = 3.8), having a positive psychiatric family history (RR = 5.3), a pre-pregnancy medical comorbidity (RR = 1.85) and a comorbid medical illness occurring during the pregnancy (RR = 2) were much likely associated with PND. Multiple linear regression analysis demonstrated that GHQ, medium- and high-risk at the HR, foreign nationality, positive family psychiatric history, and neoplastic disease before conception significantly predicted EPDS [<i>F</i>(1, 197) = 10.086, <i>R</i><sup>2</sup> = 0.324, <i>p</i> < 0.001]. <b>Limitations:</b> The sample size, poor heterogeneity in terms of socio-demographic, clinical and gynecological-obstetric characteristics, the cross-sectional design of the study. <b>Conclusions:</b> Our study showed a set of predictors associated with a higher risk for the PND onset, including gestational and pregestational medical disease. Our findings outline the need to screen all fertile women, particularly in gynecological and medical settings, in order to identify at-risk women for PND and promptly suggest a psychiatric consultation.https://www.mdpi.com/2227-9032/11/3/428perinatal depressionpostpartumpredictorspregnancy |
| spellingShingle | Laura Orsolini Simone Pompili Antonella Mauro Umberto Volpe Foreign Nationality, Family Psychiatry History and Pregestational Neoplastic Disease as Predictors of Perinatal Depression in a Cohort of Healthy Pregnant and Puerperal Women during the COVID-19 Pandemic Healthcare perinatal depression postpartum predictors pregnancy |
| title | Foreign Nationality, Family Psychiatry History and Pregestational Neoplastic Disease as Predictors of Perinatal Depression in a Cohort of Healthy Pregnant and Puerperal Women during the COVID-19 Pandemic |
| title_full | Foreign Nationality, Family Psychiatry History and Pregestational Neoplastic Disease as Predictors of Perinatal Depression in a Cohort of Healthy Pregnant and Puerperal Women during the COVID-19 Pandemic |
| title_fullStr | Foreign Nationality, Family Psychiatry History and Pregestational Neoplastic Disease as Predictors of Perinatal Depression in a Cohort of Healthy Pregnant and Puerperal Women during the COVID-19 Pandemic |
| title_full_unstemmed | Foreign Nationality, Family Psychiatry History and Pregestational Neoplastic Disease as Predictors of Perinatal Depression in a Cohort of Healthy Pregnant and Puerperal Women during the COVID-19 Pandemic |
| title_short | Foreign Nationality, Family Psychiatry History and Pregestational Neoplastic Disease as Predictors of Perinatal Depression in a Cohort of Healthy Pregnant and Puerperal Women during the COVID-19 Pandemic |
| title_sort | foreign nationality family psychiatry history and pregestational neoplastic disease as predictors of perinatal depression in a cohort of healthy pregnant and puerperal women during the covid 19 pandemic |
| topic | perinatal depression postpartum predictors pregnancy |
| url | https://www.mdpi.com/2227-9032/11/3/428 |
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