Ventilasi dan Perfusi, serta Hubungan antara Ventilasi dan Perfusi [Ventilation, Perfusion, and Its Correlation in Pulmonary Diagnostic]

Lung is a place for gas exchange where ventilation and perfusion occurs. Ventilation is the first step where sequential process of inhalation and exhalation take place. Meanwhile perfusion as the other step facilitates the gas exchange and tissue supply need. Blood flows through the lungs are equals...

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Main Authors: Afrita Amalia Laitupa, Muhammad Amin
Format: Article
Language:English
Published: Universitas Airlangga 2016-01-01
Series:Jurnal Respirasi
Subjects:
Online Access:https://e-journal.unair.ac.id/JR/article/view/12621
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author Afrita Amalia Laitupa
Muhammad Amin
author_facet Afrita Amalia Laitupa
Muhammad Amin
author_sort Afrita Amalia Laitupa
collection DOAJ
description Lung is a place for gas exchange where ventilation and perfusion occurs. Ventilation is the first step where sequential process of inhalation and exhalation take place. Meanwhile perfusion as the other step facilitates the gas exchange and tissue supply need. Blood flows through the lungs are equals as the amount of cardiac output where the factors that control cardiac output are mainly peripheral factors, also control pulmonary blood flow. In general condition, pulmonary blood vessels act as a passive tube, which can be increased with the increasing pressure and narrowed the pressure drop. Oxygen absorption level from lungs into bloodstream is a critical determinant for functional capacity, and an important factor wheter in normal conditions (including exercise) or even in illness state. Lung diffusion capacity is influenced by several geometric and functional factors. Gravitation influence systematic gradient in ventilation and perfusion distribution. Ventilation and blood flow variations at horizontal level also occur due to intrinsic anatomic variations and vascular geometry, as well as the differences in airway and vascular smooth muscle response which modifies the distribution. The change of integrity intrapleural chamber, hydrostatic pressure and osmotic imbalance, malfunction of surfactants, other intrinsic weakness of the branching system in the form of a progressive airway, and all the things that could potentially damage the structure of the lung can cause ventilation and diffusion dysfunction.
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spelling doaj.art-0377e1fdfdfa46f68c43074fed27541f2022-12-22T03:33:50ZengUniversitas AirlanggaJurnal Respirasi2407-08312621-83722016-01-01212934https://doi.org/10.20473/jr.v2-I.1.2016.29-34Ventilasi dan Perfusi, serta Hubungan antara Ventilasi dan Perfusi [Ventilation, Perfusion, and Its Correlation in Pulmonary Diagnostic]Afrita Amalia Laitupa0https://orcid.org/0000-0002-5276-282XMuhammad Amin1https://orcid.org/0000-0002-1663-1187Department of Pulmonology and Respiratory Medicine, Faculty of Medicine, Universitas Airlangga/Dr. Soetomo General Hospital, Surabaya, Indonesia.Department of Pulmonology and Respiratory Medicine, Faculty of Medicine, Universitas Airlangga/Dr. Soetomo General Hospital, Surabaya, Indonesia.Lung is a place for gas exchange where ventilation and perfusion occurs. Ventilation is the first step where sequential process of inhalation and exhalation take place. Meanwhile perfusion as the other step facilitates the gas exchange and tissue supply need. Blood flows through the lungs are equals as the amount of cardiac output where the factors that control cardiac output are mainly peripheral factors, also control pulmonary blood flow. In general condition, pulmonary blood vessels act as a passive tube, which can be increased with the increasing pressure and narrowed the pressure drop. Oxygen absorption level from lungs into bloodstream is a critical determinant for functional capacity, and an important factor wheter in normal conditions (including exercise) or even in illness state. Lung diffusion capacity is influenced by several geometric and functional factors. Gravitation influence systematic gradient in ventilation and perfusion distribution. Ventilation and blood flow variations at horizontal level also occur due to intrinsic anatomic variations and vascular geometry, as well as the differences in airway and vascular smooth muscle response which modifies the distribution. The change of integrity intrapleural chamber, hydrostatic pressure and osmotic imbalance, malfunction of surfactants, other intrinsic weakness of the branching system in the form of a progressive airway, and all the things that could potentially damage the structure of the lung can cause ventilation and diffusion dysfunction.https://e-journal.unair.ac.id/JR/article/view/12621ventilationperfusiondiffusion
spellingShingle Afrita Amalia Laitupa
Muhammad Amin
Ventilasi dan Perfusi, serta Hubungan antara Ventilasi dan Perfusi [Ventilation, Perfusion, and Its Correlation in Pulmonary Diagnostic]
Jurnal Respirasi
ventilation
perfusion
diffusion
title Ventilasi dan Perfusi, serta Hubungan antara Ventilasi dan Perfusi [Ventilation, Perfusion, and Its Correlation in Pulmonary Diagnostic]
title_full Ventilasi dan Perfusi, serta Hubungan antara Ventilasi dan Perfusi [Ventilation, Perfusion, and Its Correlation in Pulmonary Diagnostic]
title_fullStr Ventilasi dan Perfusi, serta Hubungan antara Ventilasi dan Perfusi [Ventilation, Perfusion, and Its Correlation in Pulmonary Diagnostic]
title_full_unstemmed Ventilasi dan Perfusi, serta Hubungan antara Ventilasi dan Perfusi [Ventilation, Perfusion, and Its Correlation in Pulmonary Diagnostic]
title_short Ventilasi dan Perfusi, serta Hubungan antara Ventilasi dan Perfusi [Ventilation, Perfusion, and Its Correlation in Pulmonary Diagnostic]
title_sort ventilasi dan perfusi serta hubungan antara ventilasi dan perfusi ventilation perfusion and its correlation in pulmonary diagnostic
topic ventilation
perfusion
diffusion
url https://e-journal.unair.ac.id/JR/article/view/12621
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