COMPARATIVE ANALYSIS IMMUNOTROPIC EFFECTS IN VITRO DERINAT AND SYNTHETIC TLR9 AGONIST ON RECEPTOR FUNCTION OF NEUTROPHILIC GRANULOCYTES AND MONOCYTES IN NORMAL AND INFECTIOUS PROCESS
Comparative evaluation of character of the expression of TLR9 and CD11b receptors by neutrophilic granulocytes and monocytes whole blood under the influence of Derinat and synthetic TLR9 ligand in healthy individuals and in acute infectious diseases of viral and bacterial origin has been studied. It...
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| Format: | Article |
| Language: | Russian |
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Ministry of Healthcare of the Russian Federation. “Kuban State Medical University”
2016-10-01
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| Series: | Кубанский научный медицинский вестник |
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| Online Access: | https://ksma.elpub.ru/jour/article/view/597 |
| _version_ | 1797295516188409856 |
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| author | T. V. Rusinova G. A. Chudilova N. V. Kolesnikova |
| author_facet | T. V. Rusinova G. A. Chudilova N. V. Kolesnikova |
| author_sort | T. V. Rusinova |
| collection | DOAJ |
| description | Comparative evaluation of character of the expression of TLR9 and CD11b receptors by neutrophilic granulocytes and monocytes whole blood under the influence of Derinat and synthetic TLR9 ligand in healthy individuals and in acute infectious diseases of viral and bacterial origin has been studied. It has been shown that the unidirectional effects of study drugs relate changes in the number of neutrophils, carrying TLR9, and MFI CD289 in all groups, and monocytes only in groups with infectious process. Differently directed effects identified in relation to expression of molecules CD11b monocytes in all groups, and neutrophils in a group of healthy controls. |
| first_indexed | 2024-03-07T21:49:03Z |
| format | Article |
| id | doaj.art-0382391be8c441e884f679adb7e592b2 |
| institution | Directory Open Access Journal |
| issn | 1608-6228 2541-9544 |
| language | Russian |
| last_indexed | 2024-03-07T21:49:03Z |
| publishDate | 2016-10-01 |
| publisher | Ministry of Healthcare of the Russian Federation. “Kuban State Medical University” |
| record_format | Article |
| series | Кубанский научный медицинский вестник |
| spelling | doaj.art-0382391be8c441e884f679adb7e592b22024-02-25T10:57:18ZrusMinistry of Healthcare of the Russian Federation. “Kuban State Medical University”Кубанский научный медицинский вестник1608-62282541-95442016-10-015949710.25207/1608-6228-2016-5-94-97597COMPARATIVE ANALYSIS IMMUNOTROPIC EFFECTS IN VITRO DERINAT AND SYNTHETIC TLR9 AGONIST ON RECEPTOR FUNCTION OF NEUTROPHILIC GRANULOCYTES AND MONOCYTES IN NORMAL AND INFECTIOUS PROCESST. V. Rusinova0G. A. Chudilova1N. V. Kolesnikova2ФГБОУ ВО «Кубанский государственный медицинский университет» МЗ РФФГБОУ ВО «Кубанский государственный медицинский университет» МЗ РФФГБОУ ВО «Кубанский государственный медицинский университет» МЗ РФComparative evaluation of character of the expression of TLR9 and CD11b receptors by neutrophilic granulocytes and monocytes whole blood under the influence of Derinat and synthetic TLR9 ligand in healthy individuals and in acute infectious diseases of viral and bacterial origin has been studied. It has been shown that the unidirectional effects of study drugs relate changes in the number of neutrophils, carrying TLR9, and MFI CD289 in all groups, and monocytes only in groups with infectious process. Differently directed effects identified in relation to expression of molecules CD11b monocytes in all groups, and neutrophils in a group of healthy controls.https://ksma.elpub.ru/jour/article/view/597деринатагонист tlr-9нейтрофильные гранулоцитымоноцитыderinatagonist tlr9neutrophilic granulocytesmonocytes |
| spellingShingle | T. V. Rusinova G. A. Chudilova N. V. Kolesnikova COMPARATIVE ANALYSIS IMMUNOTROPIC EFFECTS IN VITRO DERINAT AND SYNTHETIC TLR9 AGONIST ON RECEPTOR FUNCTION OF NEUTROPHILIC GRANULOCYTES AND MONOCYTES IN NORMAL AND INFECTIOUS PROCESS Кубанский научный медицинский вестник деринат агонист tlr-9 нейтрофильные гранулоциты моноциты derinat agonist tlr9 neutrophilic granulocytes monocytes |
| title | COMPARATIVE ANALYSIS IMMUNOTROPIC EFFECTS IN VITRO DERINAT AND SYNTHETIC TLR9 AGONIST ON RECEPTOR FUNCTION OF NEUTROPHILIC GRANULOCYTES AND MONOCYTES IN NORMAL AND INFECTIOUS PROCESS |
| title_full | COMPARATIVE ANALYSIS IMMUNOTROPIC EFFECTS IN VITRO DERINAT AND SYNTHETIC TLR9 AGONIST ON RECEPTOR FUNCTION OF NEUTROPHILIC GRANULOCYTES AND MONOCYTES IN NORMAL AND INFECTIOUS PROCESS |
| title_fullStr | COMPARATIVE ANALYSIS IMMUNOTROPIC EFFECTS IN VITRO DERINAT AND SYNTHETIC TLR9 AGONIST ON RECEPTOR FUNCTION OF NEUTROPHILIC GRANULOCYTES AND MONOCYTES IN NORMAL AND INFECTIOUS PROCESS |
| title_full_unstemmed | COMPARATIVE ANALYSIS IMMUNOTROPIC EFFECTS IN VITRO DERINAT AND SYNTHETIC TLR9 AGONIST ON RECEPTOR FUNCTION OF NEUTROPHILIC GRANULOCYTES AND MONOCYTES IN NORMAL AND INFECTIOUS PROCESS |
| title_short | COMPARATIVE ANALYSIS IMMUNOTROPIC EFFECTS IN VITRO DERINAT AND SYNTHETIC TLR9 AGONIST ON RECEPTOR FUNCTION OF NEUTROPHILIC GRANULOCYTES AND MONOCYTES IN NORMAL AND INFECTIOUS PROCESS |
| title_sort | comparative analysis immunotropic effects in vitro derinat and synthetic tlr9 agonist on receptor function of neutrophilic granulocytes and monocytes in normal and infectious process |
| topic | деринат агонист tlr-9 нейтрофильные гранулоциты моноциты derinat agonist tlr9 neutrophilic granulocytes monocytes |
| url | https://ksma.elpub.ru/jour/article/view/597 |
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