The Role of Hemoglobin Oxidation Products in Triggering Inflammatory Response Upon Intraventricular Hemorrhage in Premature Infants

Intraventricular hemorrhage (IVH) is a frequent complication of prematurity that is associated with high neonatal mortality and morbidity. IVH is accompanied by red blood cell (RBC) lysis, hemoglobin (Hb) oxidation, and sterile inflammation. Here we investigated whether extracellular Hb, metHb, ferr...

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Hlavní autoři: Judit Erdei, Andrea Tóth, Andrea Nagy, Benard Bogonko Nyakundi, Zsolt Fejes, Béla Nagy Jr., László Novák, László Bognár, Enikö Balogh, György Paragh, János Kappelmayer, Attila Bácsi, Viktória Jeney
Médium: Článek
Jazyk:English
Vydáno: Frontiers Media S.A. 2020-03-01
Edice:Frontiers in Immunology
Témata:
On-line přístup:https://www.frontiersin.org/article/10.3389/fimmu.2020.00228/full