Characterization and antimicrobial activity of cerium oxide nanoparticles synthesized using neem and ginger
The aim of this study is to analyze and characterize the antimicrobial effect of cerium oxide nanoparticles (NP) synthesized using neem and ginger. Finely grounded neem and ginger powder were taken and mixed with distilled water. This mixture was then heated and filtered. Ammonium cerium nitrate dis...
Main Authors: | , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Wolters Kluwer Medknow Publications
2022-01-01
|
Series: | Journal of Advanced Pharmaceutical Technology & Research |
Subjects: | |
Online Access: | http://www.japtr.org/article.asp?issn=2231-4040;year=2022;volume=13;issue=6;spage=491;epage=495;aulast=Devi |
_version_ | 1797954902152970240 |
---|---|
author | N Sanjana Devi Dhanraj M Ganapathy S Rajeshkumar Subhabrata Maiti |
author_facet | N Sanjana Devi Dhanraj M Ganapathy S Rajeshkumar Subhabrata Maiti |
author_sort | N Sanjana Devi |
collection | DOAJ |
description | The aim of this study is to analyze and characterize the antimicrobial effect of cerium oxide nanoparticles (NP) synthesized using neem and ginger. Finely grounded neem and ginger powder were taken and mixed with distilled water. This mixture was then heated and filtered. Ammonium cerium nitrate dissolved in distilled water. Both the mixtures were mixed and stirred magnetically. A double-beam ultraviolet-visible spectrophotometer was used to monitor color changes. The extract was centrifuged at 8000 rpm for 15 min. The final pellet was powdered using a hot air oven at 70°C for 24 h. Visualization was done by transmission electron microscopy and spherical morphology was noted, with an average diameter of 5 nm, in aggregated form. The sample containing 100 mg of cerium oxide shows the most significant effect on the zone of inhibition of 11 mm of Staphylococcus aureus. The results obtained in the current study confirmed that CeO-NP possessed antioxidant and cytotoxic properties. |
first_indexed | 2024-04-10T23:25:53Z |
format | Article |
id | doaj.art-0388ff96175b44b398078ff1ef7e9f3b |
institution | Directory Open Access Journal |
issn | 2231-4040 0976-2094 |
language | English |
last_indexed | 2024-04-10T23:25:53Z |
publishDate | 2022-01-01 |
publisher | Wolters Kluwer Medknow Publications |
record_format | Article |
series | Journal of Advanced Pharmaceutical Technology & Research |
spelling | doaj.art-0388ff96175b44b398078ff1ef7e9f3b2023-01-12T12:18:55ZengWolters Kluwer Medknow PublicationsJournal of Advanced Pharmaceutical Technology & Research2231-40400976-20942022-01-0113649149510.4103/japtr.japtr_196_22Characterization and antimicrobial activity of cerium oxide nanoparticles synthesized using neem and gingerN Sanjana DeviDhanraj M GanapathyS RajeshkumarSubhabrata MaitiThe aim of this study is to analyze and characterize the antimicrobial effect of cerium oxide nanoparticles (NP) synthesized using neem and ginger. Finely grounded neem and ginger powder were taken and mixed with distilled water. This mixture was then heated and filtered. Ammonium cerium nitrate dissolved in distilled water. Both the mixtures were mixed and stirred magnetically. A double-beam ultraviolet-visible spectrophotometer was used to monitor color changes. The extract was centrifuged at 8000 rpm for 15 min. The final pellet was powdered using a hot air oven at 70°C for 24 h. Visualization was done by transmission electron microscopy and spherical morphology was noted, with an average diameter of 5 nm, in aggregated form. The sample containing 100 mg of cerium oxide shows the most significant effect on the zone of inhibition of 11 mm of Staphylococcus aureus. The results obtained in the current study confirmed that CeO-NP possessed antioxidant and cytotoxic properties.http://www.japtr.org/article.asp?issn=2231-4040;year=2022;volume=13;issue=6;spage=491;epage=495;aulast=Deviceriumcharacterizationgingerinnovativenanoparticlesneem |
spellingShingle | N Sanjana Devi Dhanraj M Ganapathy S Rajeshkumar Subhabrata Maiti Characterization and antimicrobial activity of cerium oxide nanoparticles synthesized using neem and ginger Journal of Advanced Pharmaceutical Technology & Research cerium characterization ginger innovative nanoparticles neem |
title | Characterization and antimicrobial activity of cerium oxide nanoparticles synthesized using neem and ginger |
title_full | Characterization and antimicrobial activity of cerium oxide nanoparticles synthesized using neem and ginger |
title_fullStr | Characterization and antimicrobial activity of cerium oxide nanoparticles synthesized using neem and ginger |
title_full_unstemmed | Characterization and antimicrobial activity of cerium oxide nanoparticles synthesized using neem and ginger |
title_short | Characterization and antimicrobial activity of cerium oxide nanoparticles synthesized using neem and ginger |
title_sort | characterization and antimicrobial activity of cerium oxide nanoparticles synthesized using neem and ginger |
topic | cerium characterization ginger innovative nanoparticles neem |
url | http://www.japtr.org/article.asp?issn=2231-4040;year=2022;volume=13;issue=6;spage=491;epage=495;aulast=Devi |
work_keys_str_mv | AT nsanjanadevi characterizationandantimicrobialactivityofceriumoxidenanoparticlessynthesizedusingneemandginger AT dhanrajmganapathy characterizationandantimicrobialactivityofceriumoxidenanoparticlessynthesizedusingneemandginger AT srajeshkumar characterizationandantimicrobialactivityofceriumoxidenanoparticlessynthesizedusingneemandginger AT subhabratamaiti characterizationandantimicrobialactivityofceriumoxidenanoparticlessynthesizedusingneemandginger |