Characterization and antimicrobial activity of cerium oxide nanoparticles synthesized using neem and ginger

The aim of this study is to analyze and characterize the antimicrobial effect of cerium oxide nanoparticles (NP) synthesized using neem and ginger. Finely grounded neem and ginger powder were taken and mixed with distilled water. This mixture was then heated and filtered. Ammonium cerium nitrate dis...

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Main Authors: N Sanjana Devi, Dhanraj M Ganapathy, S Rajeshkumar, Subhabrata Maiti
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2022-01-01
Series:Journal of Advanced Pharmaceutical Technology & Research
Subjects:
Online Access:http://www.japtr.org/article.asp?issn=2231-4040;year=2022;volume=13;issue=6;spage=491;epage=495;aulast=Devi
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author N Sanjana Devi
Dhanraj M Ganapathy
S Rajeshkumar
Subhabrata Maiti
author_facet N Sanjana Devi
Dhanraj M Ganapathy
S Rajeshkumar
Subhabrata Maiti
author_sort N Sanjana Devi
collection DOAJ
description The aim of this study is to analyze and characterize the antimicrobial effect of cerium oxide nanoparticles (NP) synthesized using neem and ginger. Finely grounded neem and ginger powder were taken and mixed with distilled water. This mixture was then heated and filtered. Ammonium cerium nitrate dissolved in distilled water. Both the mixtures were mixed and stirred magnetically. A double-beam ultraviolet-visible spectrophotometer was used to monitor color changes. The extract was centrifuged at 8000 rpm for 15 min. The final pellet was powdered using a hot air oven at 70°C for 24 h. Visualization was done by transmission electron microscopy and spherical morphology was noted, with an average diameter of 5 nm, in aggregated form. The sample containing 100 mg of cerium oxide shows the most significant effect on the zone of inhibition of 11 mm of Staphylococcus aureus. The results obtained in the current study confirmed that CeO-NP possessed antioxidant and cytotoxic properties.
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spelling doaj.art-0388ff96175b44b398078ff1ef7e9f3b2023-01-12T12:18:55ZengWolters Kluwer Medknow PublicationsJournal of Advanced Pharmaceutical Technology & Research2231-40400976-20942022-01-0113649149510.4103/japtr.japtr_196_22Characterization and antimicrobial activity of cerium oxide nanoparticles synthesized using neem and gingerN Sanjana DeviDhanraj M GanapathyS RajeshkumarSubhabrata MaitiThe aim of this study is to analyze and characterize the antimicrobial effect of cerium oxide nanoparticles (NP) synthesized using neem and ginger. Finely grounded neem and ginger powder were taken and mixed with distilled water. This mixture was then heated and filtered. Ammonium cerium nitrate dissolved in distilled water. Both the mixtures were mixed and stirred magnetically. A double-beam ultraviolet-visible spectrophotometer was used to monitor color changes. The extract was centrifuged at 8000 rpm for 15 min. The final pellet was powdered using a hot air oven at 70°C for 24 h. Visualization was done by transmission electron microscopy and spherical morphology was noted, with an average diameter of 5 nm, in aggregated form. The sample containing 100 mg of cerium oxide shows the most significant effect on the zone of inhibition of 11 mm of Staphylococcus aureus. The results obtained in the current study confirmed that CeO-NP possessed antioxidant and cytotoxic properties.http://www.japtr.org/article.asp?issn=2231-4040;year=2022;volume=13;issue=6;spage=491;epage=495;aulast=Deviceriumcharacterizationgingerinnovativenanoparticlesneem
spellingShingle N Sanjana Devi
Dhanraj M Ganapathy
S Rajeshkumar
Subhabrata Maiti
Characterization and antimicrobial activity of cerium oxide nanoparticles synthesized using neem and ginger
Journal of Advanced Pharmaceutical Technology & Research
cerium
characterization
ginger
innovative
nanoparticles
neem
title Characterization and antimicrobial activity of cerium oxide nanoparticles synthesized using neem and ginger
title_full Characterization and antimicrobial activity of cerium oxide nanoparticles synthesized using neem and ginger
title_fullStr Characterization and antimicrobial activity of cerium oxide nanoparticles synthesized using neem and ginger
title_full_unstemmed Characterization and antimicrobial activity of cerium oxide nanoparticles synthesized using neem and ginger
title_short Characterization and antimicrobial activity of cerium oxide nanoparticles synthesized using neem and ginger
title_sort characterization and antimicrobial activity of cerium oxide nanoparticles synthesized using neem and ginger
topic cerium
characterization
ginger
innovative
nanoparticles
neem
url http://www.japtr.org/article.asp?issn=2231-4040;year=2022;volume=13;issue=6;spage=491;epage=495;aulast=Devi
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AT dhanrajmganapathy characterizationandantimicrobialactivityofceriumoxidenanoparticlessynthesizedusingneemandginger
AT srajeshkumar characterizationandantimicrobialactivityofceriumoxidenanoparticlessynthesizedusingneemandginger
AT subhabratamaiti characterizationandantimicrobialactivityofceriumoxidenanoparticlessynthesizedusingneemandginger