Is creatine a CNS neurotransmitter?
A range of experiments suggests that creatine, a molecule known for recycling ATP in muscle and brain tissue, may also function as a neurotransmitter in the central nervous system.
Main Authors: | , |
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Format: | Article |
Language: | English |
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eLife Sciences Publications Ltd
2023-10-01
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Series: | eLife |
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Online Access: | https://elifesciences.org/articles/91824 |
_version_ | 1797659155222233088 |
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author | Bhagaban Mallik C Andrew Frank |
author_facet | Bhagaban Mallik C Andrew Frank |
author_sort | Bhagaban Mallik |
collection | DOAJ |
description | A range of experiments suggests that creatine, a molecule known for recycling ATP in muscle and brain tissue, may also function as a neurotransmitter in the central nervous system. |
first_indexed | 2024-03-11T18:09:47Z |
format | Article |
id | doaj.art-038bf1304d964c9f8664989fe023b9c5 |
institution | Directory Open Access Journal |
issn | 2050-084X |
language | English |
last_indexed | 2024-03-11T18:09:47Z |
publishDate | 2023-10-01 |
publisher | eLife Sciences Publications Ltd |
record_format | Article |
series | eLife |
spelling | doaj.art-038bf1304d964c9f8664989fe023b9c52023-10-16T15:08:10ZengeLife Sciences Publications LtdeLife2050-084X2023-10-011210.7554/eLife.91824Is creatine a CNS neurotransmitter?Bhagaban Mallik0https://orcid.org/0000-0001-7637-3338C Andrew Frank1https://orcid.org/0000-0001-9599-421XDepartment of Anatomy and Cell Biology, University of Iowa, Iowa City, United StatesDepartment of Anatomy and Cell Biology, University of Iowa, Iowa City, United StatesA range of experiments suggests that creatine, a molecule known for recycling ATP in muscle and brain tissue, may also function as a neurotransmitter in the central nervous system.https://elifesciences.org/articles/91824creatineinhibitory neurotransmissionsynaptic vesiclesastrocytesSLC6A8AGAT |
spellingShingle | Bhagaban Mallik C Andrew Frank Is creatine a CNS neurotransmitter? eLife creatine inhibitory neurotransmission synaptic vesicles astrocytes SLC6A8 AGAT |
title | Is creatine a CNS neurotransmitter? |
title_full | Is creatine a CNS neurotransmitter? |
title_fullStr | Is creatine a CNS neurotransmitter? |
title_full_unstemmed | Is creatine a CNS neurotransmitter? |
title_short | Is creatine a CNS neurotransmitter? |
title_sort | is creatine a cns neurotransmitter |
topic | creatine inhibitory neurotransmission synaptic vesicles astrocytes SLC6A8 AGAT |
url | https://elifesciences.org/articles/91824 |
work_keys_str_mv | AT bhagabanmallik iscreatineacnsneurotransmitter AT candrewfrank iscreatineacnsneurotransmitter |