Long-term efficacy of aspirin desensitization in aspirin-exacerbated respiratory disease. Review of two clinical cases

Background: The aspirin exacerbated respiratory disease (AERD) shows a prevalence of 7% among asthmatics and increases to 14% in patients with difficult to control asthma. Treatment includes the use of inhibitors of leukotriene receptor (), intranasal steroids, polypectomy, asthma management accordi...

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Main Authors: Julio César Cambray-Gutiérrez, Ulises Noel García-Ramírez, Leonel Gerardo Del Rivero-Hernández, Sean Alejandro Lozano-Martínez, Patricia López-Pérez, Aurora Alejandra Chávez-García
Format: Article
Language:English
Published: Colegio Mexicano de Inmunología Clínica y Alergia, A.C. 2016-05-01
Series:Revista Alergia México
Subjects:
Online Access:http://revistaalergia.mx/ojs/index.php/ram/article/view/151
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author Julio César Cambray-Gutiérrez
Ulises Noel García-Ramírez
Leonel Gerardo Del Rivero-Hernández
Sean Alejandro Lozano-Martínez
Patricia López-Pérez
Aurora Alejandra Chávez-García
author_facet Julio César Cambray-Gutiérrez
Ulises Noel García-Ramírez
Leonel Gerardo Del Rivero-Hernández
Sean Alejandro Lozano-Martínez
Patricia López-Pérez
Aurora Alejandra Chávez-García
author_sort Julio César Cambray-Gutiérrez
collection DOAJ
description Background: The aspirin exacerbated respiratory disease (AERD) shows a prevalence of 7% among asthmatics and increases to 14% in patients with difficult to control asthma. Treatment includes the use of inhibitors of leukotriene receptor (), intranasal steroids, polypectomy, asthma management according to the severity and avoid taking nonsteroidal anti-inflammatory drugs (NSAIDs). In some patients it is necessary desensitization protocol to it. Clinical cases: two patients diagnosed with respiratory disease exacerbated by aspirin, with poor asthma control and need for multiple polypectomies, despite optimal pharmacological management, carrying out protocol desensitization to aspirin (AAS) successful, now after 4 years of having carried out, they have adequate asthma control without need for polypectomies with a maintenance dose of aspirin 150 mg/day.
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spelling doaj.art-038cca0a7d4449f6878e193a927e55b22023-09-02T12:04:43ZengColegio Mexicano de Inmunología Clínica y Alergia, A.C.Revista Alergia México0002-51512448-91902016-05-0163220721210.29262/ram.v63i2.151120Long-term efficacy of aspirin desensitization in aspirin-exacerbated respiratory disease. Review of two clinical casesJulio César Cambray-Gutiérrez0Ulises Noel García-Ramírez1Leonel Gerardo Del Rivero-Hernández2Sean Alejandro Lozano-Martínez3Patricia López-Pérez4Aurora Alejandra Chávez-García5Instituto Mexicano del Seguro Social, Centro Médico Nacional Siglo XXI, Hospital de Especialidades, Servicio de Alergia e Inmunología Clínica, Ciudad de MéxicoInstituto Mexicano del Seguro Social, Centro Médico Nacional del Bajío, Hospital de Especialidades, León, GuanajuatoInstituto Mexicano del Seguro Social, Centro Médico Nacional Siglo XXI, Hospital de Especialidades, Servicio de Alergia e Inmunología Clínica, Ciudad de MéxicoInstituto Mexicano del Seguro Social, Centro Médico Nacional del Bajío, Hospital de Especialidades, León, GuanajuatoInstituto Mexicano del Seguro Social, Centro Médico Nacional Siglo XXI, Hospital de Especialidades, Servicio de Alergia e Inmunología Clínica, Ciudad de MéxicoInstituto Mexicano del Seguro Social, Centro Médico Nacional Siglo XXI, Hospital de Especialidades, Servicio de Alergia e Inmunología Clínica, Ciudad de MéxicoBackground: The aspirin exacerbated respiratory disease (AERD) shows a prevalence of 7% among asthmatics and increases to 14% in patients with difficult to control asthma. Treatment includes the use of inhibitors of leukotriene receptor (), intranasal steroids, polypectomy, asthma management according to the severity and avoid taking nonsteroidal anti-inflammatory drugs (NSAIDs). In some patients it is necessary desensitization protocol to it. Clinical cases: two patients diagnosed with respiratory disease exacerbated by aspirin, with poor asthma control and need for multiple polypectomies, despite optimal pharmacological management, carrying out protocol desensitization to aspirin (AAS) successful, now after 4 years of having carried out, they have adequate asthma control without need for polypectomies with a maintenance dose of aspirin 150 mg/day.http://revistaalergia.mx/ojs/index.php/ram/article/view/151enfermedad respiratoriaaspirinadesensibilización
spellingShingle Julio César Cambray-Gutiérrez
Ulises Noel García-Ramírez
Leonel Gerardo Del Rivero-Hernández
Sean Alejandro Lozano-Martínez
Patricia López-Pérez
Aurora Alejandra Chávez-García
Long-term efficacy of aspirin desensitization in aspirin-exacerbated respiratory disease. Review of two clinical cases
Revista Alergia México
enfermedad respiratoria
aspirina
desensibilización
title Long-term efficacy of aspirin desensitization in aspirin-exacerbated respiratory disease. Review of two clinical cases
title_full Long-term efficacy of aspirin desensitization in aspirin-exacerbated respiratory disease. Review of two clinical cases
title_fullStr Long-term efficacy of aspirin desensitization in aspirin-exacerbated respiratory disease. Review of two clinical cases
title_full_unstemmed Long-term efficacy of aspirin desensitization in aspirin-exacerbated respiratory disease. Review of two clinical cases
title_short Long-term efficacy of aspirin desensitization in aspirin-exacerbated respiratory disease. Review of two clinical cases
title_sort long term efficacy of aspirin desensitization in aspirin exacerbated respiratory disease review of two clinical cases
topic enfermedad respiratoria
aspirina
desensibilización
url http://revistaalergia.mx/ojs/index.php/ram/article/view/151
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