Influence of Dry Eye Disease on the Measurement Repeatability of Corneal Curvature Radius and Axial Length in Patients with Cataract
The influence of dry eye disease (DED) on ocular biometric measurements is unclear. We aimed to investigate the effect of DED on the repeatability of ocular biometric measurements in cataract patients. Overall, 114 eyes scheduled for cataract surgery were enrolled. Before surgery, DED parameters inc...
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MDPI AG
2022-01-01
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| Series: | Journal of Clinical Medicine |
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| Online Access: | https://www.mdpi.com/2077-0383/11/3/710 |
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| author | Takahiro Hiraoka Hiroki Asano Tomohiro Ogami Shinichiro Nakano Yoshifumi Okamoto Yoshiaki Yamada Tetsuro Oshika |
| author_facet | Takahiro Hiraoka Hiroki Asano Tomohiro Ogami Shinichiro Nakano Yoshifumi Okamoto Yoshiaki Yamada Tetsuro Oshika |
| author_sort | Takahiro Hiraoka |
| collection | DOAJ |
| description | The influence of dry eye disease (DED) on ocular biometric measurements is unclear. We aimed to investigate the effect of DED on the repeatability of ocular biometric measurements in cataract patients. Overall, 114 eyes scheduled for cataract surgery were enrolled. Before surgery, DED parameters including tear film break-up time (BUT), corneal and conjunctival staining scores, and subjective symptoms were examined. Corneal curvature radius and axial length were assessed twice on the same day using IOLMaster-500 (Carl Zeiss Meditec), and the absolute difference between the two measurements was calculated and used as an index of measurement repeatability. The measurement repeatability of the steep meridian of corneal curvature radius was significantly worse in eyes with DED than in those without DED (<i>p</i> = 0.044) and was significantly associated with BUT (r = −0.206, <i>p</i> = 0.031). The measurement repeatability of axial length was negatively correlated with BUT (r = −0.199, <i>p</i> = 0.041) and positively correlated with the corneal staining score (r = 0.253, <i>p</i> = 0.009). In conclusion, the measurement repeatability of corneal curvature radius declined in eyes with DED. Shortened BUTs were associated with a deterioration in the measurement repeatability of corneal curvature radius and axial length. |
| first_indexed | 2024-03-09T23:40:31Z |
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| id | doaj.art-038da602d725410ba4d9a4440a9dc3be |
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| issn | 2077-0383 |
| language | English |
| last_indexed | 2024-03-09T23:40:31Z |
| publishDate | 2022-01-01 |
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| series | Journal of Clinical Medicine |
| spelling | doaj.art-038da602d725410ba4d9a4440a9dc3be2023-11-23T16:52:46ZengMDPI AGJournal of Clinical Medicine2077-03832022-01-0111371010.3390/jcm11030710Influence of Dry Eye Disease on the Measurement Repeatability of Corneal Curvature Radius and Axial Length in Patients with CataractTakahiro Hiraoka0Hiroki Asano1Tomohiro Ogami2Shinichiro Nakano3Yoshifumi Okamoto4Yoshiaki Yamada5Tetsuro Oshika6Department of Ophthalmology, Faculty of Medicine, University of Tsukuba, Tsukuba 305-8575, JapanDepartment of Ophthalmology, Tsuchiura Kyodo General Hospital Namegata District Medical Center, Tsuchiura 311-3516, JapanDepartment of Ophthalmology, Ibaraki Seinan Medical Center Hospital, Sakai 306-0433, JapanDepartment of Ophthalmology, Ryugasaki Saiseikai Hospital, Ryugasaki 301-0854, JapanDepartment of Ophthalmology, Faculty of Medicine, University of Tsukuba, Tsukuba 305-8575, JapanJapan Medical Affairs, Development Management Department, Japan Business, Santen Pharmaceutical Co., Ltd., Osaka 530-8552, JapanDepartment of Ophthalmology, Faculty of Medicine, University of Tsukuba, Tsukuba 305-8575, JapanThe influence of dry eye disease (DED) on ocular biometric measurements is unclear. We aimed to investigate the effect of DED on the repeatability of ocular biometric measurements in cataract patients. Overall, 114 eyes scheduled for cataract surgery were enrolled. Before surgery, DED parameters including tear film break-up time (BUT), corneal and conjunctival staining scores, and subjective symptoms were examined. Corneal curvature radius and axial length were assessed twice on the same day using IOLMaster-500 (Carl Zeiss Meditec), and the absolute difference between the two measurements was calculated and used as an index of measurement repeatability. The measurement repeatability of the steep meridian of corneal curvature radius was significantly worse in eyes with DED than in those without DED (<i>p</i> = 0.044) and was significantly associated with BUT (r = −0.206, <i>p</i> = 0.031). The measurement repeatability of axial length was negatively correlated with BUT (r = −0.199, <i>p</i> = 0.041) and positively correlated with the corneal staining score (r = 0.253, <i>p</i> = 0.009). In conclusion, the measurement repeatability of corneal curvature radius declined in eyes with DED. Shortened BUTs were associated with a deterioration in the measurement repeatability of corneal curvature radius and axial length.https://www.mdpi.com/2077-0383/11/3/710dry eye diseasecataract surgerybiometryrepeatabilitycorneal curvature radiusaxial length |
| spellingShingle | Takahiro Hiraoka Hiroki Asano Tomohiro Ogami Shinichiro Nakano Yoshifumi Okamoto Yoshiaki Yamada Tetsuro Oshika Influence of Dry Eye Disease on the Measurement Repeatability of Corneal Curvature Radius and Axial Length in Patients with Cataract Journal of Clinical Medicine dry eye disease cataract surgery biometry repeatability corneal curvature radius axial length |
| title | Influence of Dry Eye Disease on the Measurement Repeatability of Corneal Curvature Radius and Axial Length in Patients with Cataract |
| title_full | Influence of Dry Eye Disease on the Measurement Repeatability of Corneal Curvature Radius and Axial Length in Patients with Cataract |
| title_fullStr | Influence of Dry Eye Disease on the Measurement Repeatability of Corneal Curvature Radius and Axial Length in Patients with Cataract |
| title_full_unstemmed | Influence of Dry Eye Disease on the Measurement Repeatability of Corneal Curvature Radius and Axial Length in Patients with Cataract |
| title_short | Influence of Dry Eye Disease on the Measurement Repeatability of Corneal Curvature Radius and Axial Length in Patients with Cataract |
| title_sort | influence of dry eye disease on the measurement repeatability of corneal curvature radius and axial length in patients with cataract |
| topic | dry eye disease cataract surgery biometry repeatability corneal curvature radius axial length |
| url | https://www.mdpi.com/2077-0383/11/3/710 |
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