Age dependent contribution of entry via the CSF to the overall brain entry of small and large hydrophilic markers

Age dependent contribution of entry via the CSF to the overall brain entry of small and large hydrophilic markers

Abstract Background Apparent permeability of the blood brain barrier to hydrophilic markers has been shown to be higher in the developing brain. Apart from synthesis in situ, any substance detected in the brain parenchyma can originate from two sources: directly through blood vessels of brain vascul...

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Bibliographic Details
Main Authors:	Fiona Qiu, Yifan Huang, Norman R. Saunders, Mark D. Habgood, Katarzyna M. Dziegielewska
Format:	Article
Language:	English
Published:	BMC 2022-11-01
Series:	Fluids and Barriers of the CNS
Subjects:	Cerebrospinal fluid, CSF Brain Development Sucrose Dextran Blood brain barrier, BBB
Online Access:	https://doi.org/10.1186/s12987-022-00387-z

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