The impact of antimicrobial stewardship programs on the appropriateness of prophylaxis and antimicrobial therapy: the experience of the “F. Miulli” Hospital of Bari
Introduction: The continuous increase of antimicrobial resistance (AMR) requires antimicrobial stewardship programs (ASPs) to optimize antimicrobial use, including selection, dose, duration, and way of administration. Methods and Results: An “Antimicrobial Stewardship Team” (AST) was established a...
| Main Authors: | , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
AboutScience Srl
2021-02-01
|
| Series: | AboutOpen |
| Subjects: | |
| Online Access: | https://journals.aboutscience.eu/index.php/aboutopen/article/view/2199 |
| _version_ | 1818876281949782016 |
|---|---|
| author | Vincenzo Picerno Gisella Caracciolo Martina Cortelletti Maurizio Formoso Vincenzo Longobardo Angela Moramarco Fabrizio Celani |
| author_facet | Vincenzo Picerno Gisella Caracciolo Martina Cortelletti Maurizio Formoso Vincenzo Longobardo Angela Moramarco Fabrizio Celani |
| author_sort | Vincenzo Picerno |
| collection | DOAJ |
| description | Introduction: The continuous increase of antimicrobial resistance (AMR) requires antimicrobial stewardship programs (ASPs) to optimize antimicrobial use, including selection, dose, duration, and way of administration.
Methods and Results: An “Antimicrobial Stewardship Team” (AST) was established at “F. Miulli” Hospital of Bari. The AST is a multidisciplinary group formed by a pharmacist, an infectious disease specialist, a microbiologist, an anesthetist and a hygienist. The AST has started a clinical path of professional interactions and optimization of antimicrobial use. The AST was focused on surgical antibiotic prophylaxis, planning events/meetings with 13 wards of “F. Miulli” hospital and writing 13 operating guidelines. The AST was focused on antimicrobial therapies too. On this occasion, the AST did not organize events or meetings but was focused on professional interactions with clinicians to optimize the antimicrobial use in the treatment of multi-drug resistant (MDR) pathogens. A reduction of antimicrobial use (defined daily dose, DDD) and pharmaceutical expenditure was reached in surgical wards during 2017-2018, while, in the same period, an increase of antimicrobial use (DDD) and pharmaceutical expenditure was observed in non-surgical wards.
Conclusions: The “Antimicrobial Stewardship Team” programs are essential to monitor the hospital economic resources and to support the purchase of the innovative antimicrobial therapies to treat multi-drug resistant pathogens. |
| first_indexed | 2024-12-19T13:39:54Z |
| format | Article |
| id | doaj.art-03904165a2db495dba9d7e3219a575ce |
| institution | Directory Open Access Journal |
| issn | 2465-2628 |
| language | English |
| last_indexed | 2024-12-19T13:39:54Z |
| publishDate | 2021-02-01 |
| publisher | AboutScience Srl |
| record_format | Article |
| series | AboutOpen |
| spelling | doaj.art-03904165a2db495dba9d7e3219a575ce2022-12-21T20:19:02ZengAboutScience SrlAboutOpen2465-26282021-02-018110.33393/ao.2021.2199The impact of antimicrobial stewardship programs on the appropriateness of prophylaxis and antimicrobial therapy: the experience of the “F. Miulli” Hospital of BariVincenzo Picerno0Gisella Caracciolo1Martina Cortelletti2Maurizio Formoso3Vincenzo Longobardo4Angela Moramarco5Fabrizio Celani6UOC Farmacia Ospedaliera, Ente Ecclesiastico Ospedale Generale Regionale “F. Miulli”, Acquaviva delle Fonti, Bari - ItalyUOC Anestesia e Rianimazione, Ente Ecclesiastico Ospedale Generale Regionale “F. Miulli”, Acquaviva delle Fonti, Bari - ItalyUOC Farmacia Ospedaliera, Ente Ecclesiastico Ospedale Generale Regionale “F. Miulli”, Acquaviva delle Fonti, Bari - ItalyDirezione Sanitaria, Ente Ecclesiastico Ospedale Generale Regionale “F. Miulli”, Acquaviva delle Fonti, Bari - ItalyUOC Medicina Interna, Ente Ecclesiastico Ospedale Generale Regionale “F. Miulli”, Acquaviva delle Fonti, Bari - ItalyUOC Patologia Clinica, Ente Ecclesiastico Ospedale Generale Regionale “F. Miulli”, Acquaviva delle Fonti, Bari - ItalyDirettore Sanitario, Ente Ecclesiastico Ospedale Generale Regionale “F. Miulli”, Acquaviva delle Fonti, Bari - ItalyIntroduction: The continuous increase of antimicrobial resistance (AMR) requires antimicrobial stewardship programs (ASPs) to optimize antimicrobial use, including selection, dose, duration, and way of administration. Methods and Results: An “Antimicrobial Stewardship Team” (AST) was established at “F. Miulli” Hospital of Bari. The AST is a multidisciplinary group formed by a pharmacist, an infectious disease specialist, a microbiologist, an anesthetist and a hygienist. The AST has started a clinical path of professional interactions and optimization of antimicrobial use. The AST was focused on surgical antibiotic prophylaxis, planning events/meetings with 13 wards of “F. Miulli” hospital and writing 13 operating guidelines. The AST was focused on antimicrobial therapies too. On this occasion, the AST did not organize events or meetings but was focused on professional interactions with clinicians to optimize the antimicrobial use in the treatment of multi-drug resistant (MDR) pathogens. A reduction of antimicrobial use (defined daily dose, DDD) and pharmaceutical expenditure was reached in surgical wards during 2017-2018, while, in the same period, an increase of antimicrobial use (DDD) and pharmaceutical expenditure was observed in non-surgical wards. Conclusions: The “Antimicrobial Stewardship Team” programs are essential to monitor the hospital economic resources and to support the purchase of the innovative antimicrobial therapies to treat multi-drug resistant pathogens.https://journals.aboutscience.eu/index.php/aboutopen/article/view/2199Antimicrobial stewardshipAntimicrobial stewardship programsMultidisciplinary groupSurgical wards |
| spellingShingle | Vincenzo Picerno Gisella Caracciolo Martina Cortelletti Maurizio Formoso Vincenzo Longobardo Angela Moramarco Fabrizio Celani The impact of antimicrobial stewardship programs on the appropriateness of prophylaxis and antimicrobial therapy: the experience of the “F. Miulli” Hospital of Bari AboutOpen Antimicrobial stewardship Antimicrobial stewardship programs Multidisciplinary group Surgical wards |
| title | The impact of antimicrobial stewardship programs on the appropriateness of prophylaxis and antimicrobial therapy: the experience of the “F. Miulli” Hospital of Bari |
| title_full | The impact of antimicrobial stewardship programs on the appropriateness of prophylaxis and antimicrobial therapy: the experience of the “F. Miulli” Hospital of Bari |
| title_fullStr | The impact of antimicrobial stewardship programs on the appropriateness of prophylaxis and antimicrobial therapy: the experience of the “F. Miulli” Hospital of Bari |
| title_full_unstemmed | The impact of antimicrobial stewardship programs on the appropriateness of prophylaxis and antimicrobial therapy: the experience of the “F. Miulli” Hospital of Bari |
| title_short | The impact of antimicrobial stewardship programs on the appropriateness of prophylaxis and antimicrobial therapy: the experience of the “F. Miulli” Hospital of Bari |
| title_sort | impact of antimicrobial stewardship programs on the appropriateness of prophylaxis and antimicrobial therapy the experience of the f miulli hospital of bari |
| topic | Antimicrobial stewardship Antimicrobial stewardship programs Multidisciplinary group Surgical wards |
| url | https://journals.aboutscience.eu/index.php/aboutopen/article/view/2199 |
| work_keys_str_mv | AT vincenzopicerno theimpactofantimicrobialstewardshipprogramsontheappropriatenessofprophylaxisandantimicrobialtherapytheexperienceofthefmiullihospitalofbari AT gisellacaracciolo theimpactofantimicrobialstewardshipprogramsontheappropriatenessofprophylaxisandantimicrobialtherapytheexperienceofthefmiullihospitalofbari AT martinacortelletti theimpactofantimicrobialstewardshipprogramsontheappropriatenessofprophylaxisandantimicrobialtherapytheexperienceofthefmiullihospitalofbari AT maurizioformoso theimpactofantimicrobialstewardshipprogramsontheappropriatenessofprophylaxisandantimicrobialtherapytheexperienceofthefmiullihospitalofbari AT vincenzolongobardo theimpactofantimicrobialstewardshipprogramsontheappropriatenessofprophylaxisandantimicrobialtherapytheexperienceofthefmiullihospitalofbari AT angelamoramarco theimpactofantimicrobialstewardshipprogramsontheappropriatenessofprophylaxisandantimicrobialtherapytheexperienceofthefmiullihospitalofbari AT fabriziocelani theimpactofantimicrobialstewardshipprogramsontheappropriatenessofprophylaxisandantimicrobialtherapytheexperienceofthefmiullihospitalofbari AT vincenzopicerno impactofantimicrobialstewardshipprogramsontheappropriatenessofprophylaxisandantimicrobialtherapytheexperienceofthefmiullihospitalofbari AT gisellacaracciolo impactofantimicrobialstewardshipprogramsontheappropriatenessofprophylaxisandantimicrobialtherapytheexperienceofthefmiullihospitalofbari AT martinacortelletti impactofantimicrobialstewardshipprogramsontheappropriatenessofprophylaxisandantimicrobialtherapytheexperienceofthefmiullihospitalofbari AT maurizioformoso impactofantimicrobialstewardshipprogramsontheappropriatenessofprophylaxisandantimicrobialtherapytheexperienceofthefmiullihospitalofbari AT vincenzolongobardo impactofantimicrobialstewardshipprogramsontheappropriatenessofprophylaxisandantimicrobialtherapytheexperienceofthefmiullihospitalofbari AT angelamoramarco impactofantimicrobialstewardshipprogramsontheappropriatenessofprophylaxisandantimicrobialtherapytheexperienceofthefmiullihospitalofbari AT fabriziocelani impactofantimicrobialstewardshipprogramsontheappropriatenessofprophylaxisandantimicrobialtherapytheexperienceofthefmiullihospitalofbari |