Does Calorie Restriction Modulate Inflammaging via FoxO Transcription Factors?

Does Calorie Restriction Modulate Inflammaging via FoxO Transcription Factors?

Calorie restriction (CR) has been shown to extend lifespan and retard aging-related functional decline in animals. Previously, we found that the anti-neoplastic and lifespan-extending effects of CR in mice are regulated by forkhead box O transcription factors (FoxO1 and FoxO3), located downstream of...

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Bibliographic Details
Main Authors: Sang-Eun Kim, Ryoichi Mori, Isao Shimokawa
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:Nutrients
Subjects:
calorie restriction
FoxO
inflammaging
NLRP3 inflammasome
cellular senescence
Online Access:https://www.mdpi.com/2072-6643/12/7/1959

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