Preventing Complications in Pregnant Women with Mild and Moderate Severity of Acute Respiratory Infections
Relevance. Pregnant women are often exposed to respiratory viruses. Occasionally, the fetus may be harmed by the virus.Goal to present materials revealing the safety and effectiveness of local interferon therapy used in the initial stage of acute respiratory infection in pregnant women from 14 weeks...
| Main Authors: | , , , , , , , , , , , |
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| Format: | Article |
| Language: | Russian |
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Numikom LLC
2018-02-01
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| Series: | Эпидемиология и вакцинопрофилактика |
| Subjects: | |
| Online Access: | https://www.epidemvac.ru/jour/article/view/404 |
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| author | M. P. Kostinov I. V. Lukachev A. K. Meshcheryakova O. O. Magarshak V. B. Polischuk E. B. Faizuloev T. S. Guseva O. V. Parshina S. V. Novikova M. A. Ignatieva A. A. Savisko N. I. Brico |
| author_facet | M. P. Kostinov I. V. Lukachev A. K. Meshcheryakova O. O. Magarshak V. B. Polischuk E. B. Faizuloev T. S. Guseva O. V. Parshina S. V. Novikova M. A. Ignatieva A. A. Savisko N. I. Brico |
| author_sort | M. P. Kostinov |
| collection | DOAJ |
| description | Relevance. Pregnant women are often exposed to respiratory viruses. Occasionally, the fetus may be harmed by the virus.Goal to present materials revealing the safety and effectiveness of local interferon therapy used in the initial stage of acute respiratory infection in pregnant women from 14 weeks of gestation.Materials and methods. An in-depth analysis of the results of a study of the safety and efficacy of local interferon-therapy of respiratory infections presented in more than 60 literature sources, and own research.Results. It is shown that the inclusion of interferon-α2b (Viferon®) preparation in the complex of basic ARI therapy in pregnant women leads to a decrease in the content in the nasal washout of IL-8, the growth of T-lymphocytes and T-helpers, a more pronounced tendency to decrease natural killers; positively affects the microbiocenosis of the mucous membranes of the upper respiratory tract; leads to a reduction in symptoms of acute pharyngitis, bacterial complications from the upper respiratory tract and, as a consequence, minimizes the need for systemic antibacterial therapy.Conclusions. The conclusion is made about the expediency of including the recombinant interferon-α2b (Viferon®) preparation in intranasal gel form in the complex of basic ARI therapy in pregnant women. |
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| format | Article |
| id | doaj.art-03938026c3264c189cf446bfc75ff3d9 |
| institution | Directory Open Access Journal |
| issn | 2073-3046 2619-0494 |
| language | Russian |
| last_indexed | 2025-03-14T11:07:37Z |
| publishDate | 2018-02-01 |
| publisher | Numikom LLC |
| record_format | Article |
| series | Эпидемиология и вакцинопрофилактика |
| spelling | doaj.art-03938026c3264c189cf446bfc75ff3d92025-03-02T10:40:29ZrusNumikom LLCЭпидемиология и вакцинопрофилактика2073-30462619-04942018-02-01171627310.31631/2073-3046-2018-17-1-62-73402Preventing Complications in Pregnant Women with Mild and Moderate Severity of Acute Respiratory InfectionsM. P. Kostinov0I. V. Lukachev1A. K. Meshcheryakova2O. O. Magarshak3V. B. Polischuk4E. B. Faizuloev5T. S. Guseva6O. V. Parshina7S. V. Novikova8M. A. Ignatieva9A. A. Savisko10N. I. Brico11I. I. Mechnikov Research Institute of Vaccines and Sera of Russian Academy of Sciences; Federal State Autonomous Educational Institution of Higher Education I. M. Sechenov First Moscow State Medical University of the Ministry of Health of the Russian FederationI. I. Mechnikov Research Institute of Vaccines and Sera of Russian Academy of SciencesI. I. Mechnikov Research Institute of Vaccines and Sera of Russian Academy of SciencesI. I. Mechnikov Research Institute of Vaccines and Sera of Russian Academy of SciencesI. I. Mechnikov Research Institute of Vaccines and Sera of Russian Academy of SciencesI. I. Mechnikov Research Institute of Vaccines and Sera of Russian Academy of SciencesFederal State Budget Institution «N. F. Gamaleya Federal Centre of Epidemiology and Microbiology» of the Ministry of Healthcare of the Russian FederationFederal State Budget Institution «N. F. Gamaleya Federal Centre of Epidemiology and Microbiology» of the Ministry of Healthcare of the Russian FederationState Budgetary Institution of Public Health of Moscow region «Moscow Regional Research Institute of Obstetrics and Gynecology» of the Ministry of Healthcare of the Moscow regionState Budgetary Institution of Public Health of Moscow region «Moscow Regional Research Institute of Obstetrics and Gynecology» of the Ministry of Healthcare of the Moscow regionState Budgetary Educational Institution of Higher Professional Training «Rostov State Medical University» of the Ministry of Healthcare of the Russian FederationFederal State Autonomous Educational Institution of Higher Education I. M. Sechenov First Moscow State Medical University of the Ministry of Health of the Russian FederationRelevance. Pregnant women are often exposed to respiratory viruses. Occasionally, the fetus may be harmed by the virus.Goal to present materials revealing the safety and effectiveness of local interferon therapy used in the initial stage of acute respiratory infection in pregnant women from 14 weeks of gestation.Materials and methods. An in-depth analysis of the results of a study of the safety and efficacy of local interferon-therapy of respiratory infections presented in more than 60 literature sources, and own research.Results. It is shown that the inclusion of interferon-α2b (Viferon®) preparation in the complex of basic ARI therapy in pregnant women leads to a decrease in the content in the nasal washout of IL-8, the growth of T-lymphocytes and T-helpers, a more pronounced tendency to decrease natural killers; positively affects the microbiocenosis of the mucous membranes of the upper respiratory tract; leads to a reduction in symptoms of acute pharyngitis, bacterial complications from the upper respiratory tract and, as a consequence, minimizes the need for systemic antibacterial therapy.Conclusions. The conclusion is made about the expediency of including the recombinant interferon-α2b (Viferon®) preparation in intranasal gel form in the complex of basic ARI therapy in pregnant women.https://www.epidemvac.ru/jour/article/view/404acute respiratory infectionspregnantrecombinant interferon-α2b |
| spellingShingle | M. P. Kostinov I. V. Lukachev A. K. Meshcheryakova O. O. Magarshak V. B. Polischuk E. B. Faizuloev T. S. Guseva O. V. Parshina S. V. Novikova M. A. Ignatieva A. A. Savisko N. I. Brico Preventing Complications in Pregnant Women with Mild and Moderate Severity of Acute Respiratory Infections Эпидемиология и вакцинопрофилактика acute respiratory infections pregnant recombinant interferon-α2b |
| title | Preventing Complications in Pregnant Women with Mild and Moderate Severity of Acute Respiratory Infections |
| title_full | Preventing Complications in Pregnant Women with Mild and Moderate Severity of Acute Respiratory Infections |
| title_fullStr | Preventing Complications in Pregnant Women with Mild and Moderate Severity of Acute Respiratory Infections |
| title_full_unstemmed | Preventing Complications in Pregnant Women with Mild and Moderate Severity of Acute Respiratory Infections |
| title_short | Preventing Complications in Pregnant Women with Mild and Moderate Severity of Acute Respiratory Infections |
| title_sort | preventing complications in pregnant women with mild and moderate severity of acute respiratory infections |
| topic | acute respiratory infections pregnant recombinant interferon-α2b |
| url | https://www.epidemvac.ru/jour/article/view/404 |
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