Binge Eating and Compulsive Buying During Cabergoline Treatment for Prolactinoma: A Case Report
Prolactinomas are the most prevalent functional pituitary adenomas. They are usually treated clinically with dopamine agonists. The most widely used and suitable drug is cabergoline (CAB), a specific D2 dopamine agonists. Patients in prolactinoma treatment with CAB commonly report physical side effe...
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2022-05-01
|
| Series: | Frontiers in Psychiatry |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fpsyt.2022.844718/full |
| _version_ | 1811256553845555200 |
|---|---|
| author | Ana Carolina Correa e Castro Andressa Alexandre de Araujo Mariana Coelho Botelho João Bosco Nascimento Rafaela Marchon de Souza Monica Roberto Gadelha Antonio E. Nardi Alice Helena Dutra Violante |
| author_facet | Ana Carolina Correa e Castro Andressa Alexandre de Araujo Mariana Coelho Botelho João Bosco Nascimento Rafaela Marchon de Souza Monica Roberto Gadelha Antonio E. Nardi Alice Helena Dutra Violante |
| author_sort | Ana Carolina Correa e Castro |
| collection | DOAJ |
| description | Prolactinomas are the most prevalent functional pituitary adenomas. They are usually treated clinically with dopamine agonists. The most widely used and suitable drug is cabergoline (CAB), a specific D2 dopamine agonists. Patients in prolactinoma treatment with CAB commonly report physical side effects, but aberrant behavioral changes such as increased impulsivity have also been reported recently. We report the case of a 47-year-old Brazilian woman with prolactinoma that developed compulsive buying, binge eating, and hypersexuality after four years of CAB treatment. In her psychiatric evaluation, the patient scored high levels on the following scales: Compulsive Buying Scale (CBS), Binge Eating Scale (BES), and Barratt Impulsiveness Scale-11 (BIS11). She also reported financial problems and weight gain in addition to her social and clinical problems. Impulsivity disorders may appear with the use of CAB and other dopamine agonists. We suggest that more observational studies with a large patient sample and specific regular psychiatric evaluations during treatment are necessary for patients in use of CAB, especially those treated for several years. |
| first_indexed | 2024-04-12T17:42:02Z |
| format | Article |
| id | doaj.art-0397c165ce4d4ade8c9c535c8a16f468 |
| institution | Directory Open Access Journal |
| issn | 1664-0640 |
| language | English |
| last_indexed | 2024-04-12T17:42:02Z |
| publishDate | 2022-05-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Psychiatry |
| spelling | doaj.art-0397c165ce4d4ade8c9c535c8a16f4682022-12-22T03:22:46ZengFrontiers Media S.A.Frontiers in Psychiatry1664-06402022-05-011310.3389/fpsyt.2022.844718844718Binge Eating and Compulsive Buying During Cabergoline Treatment for Prolactinoma: A Case ReportAna Carolina Correa e Castro0Andressa Alexandre de Araujo1Mariana Coelho Botelho2João Bosco Nascimento3Rafaela Marchon de Souza4Monica Roberto Gadelha5Antonio E. Nardi6Alice Helena Dutra Violante7Institute of Psychiatry, Federal University of Rio de Janeiro, Rio de Janeiro, BrazilFederal University of Rio de Janeiro, Rio de Janeiro, BrazilUFRJ Scientific Initiation Program (a) and Rio de Janeiro State Research Foundation (b), Rio de Janeiro, BrazilUFRJ Scientific Initiation Program (a) and Rio de Janeiro State Research Foundation (b), Rio de Janeiro, BrazilUFRJ Scientific Initiation Program (a) and Rio de Janeiro State Research Foundation (b), Rio de Janeiro, BrazilEndocrinology, Federal University of Rio de Janeiro School of Medicine, Rio de Janeiro, BrazilFull Professor of Psychiatry, Federal University of Rio de Janeiro School of Medicine, Instituto de Psquiatria da Federal University of Rio de Janeiro, Rio de Janeiro, BrazilEndocrinology, Federal University of Rio de Janeiro School of Medicine, Rio de Janeiro, BrazilProlactinomas are the most prevalent functional pituitary adenomas. They are usually treated clinically with dopamine agonists. The most widely used and suitable drug is cabergoline (CAB), a specific D2 dopamine agonists. Patients in prolactinoma treatment with CAB commonly report physical side effects, but aberrant behavioral changes such as increased impulsivity have also been reported recently. We report the case of a 47-year-old Brazilian woman with prolactinoma that developed compulsive buying, binge eating, and hypersexuality after four years of CAB treatment. In her psychiatric evaluation, the patient scored high levels on the following scales: Compulsive Buying Scale (CBS), Binge Eating Scale (BES), and Barratt Impulsiveness Scale-11 (BIS11). She also reported financial problems and weight gain in addition to her social and clinical problems. Impulsivity disorders may appear with the use of CAB and other dopamine agonists. We suggest that more observational studies with a large patient sample and specific regular psychiatric evaluations during treatment are necessary for patients in use of CAB, especially those treated for several years.https://www.frontiersin.org/articles/10.3389/fpsyt.2022.844718/fullprolactinomacabergolineimpulsivitycompulsive behaviorcase report |
| spellingShingle | Ana Carolina Correa e Castro Andressa Alexandre de Araujo Mariana Coelho Botelho João Bosco Nascimento Rafaela Marchon de Souza Monica Roberto Gadelha Antonio E. Nardi Alice Helena Dutra Violante Binge Eating and Compulsive Buying During Cabergoline Treatment for Prolactinoma: A Case Report Frontiers in Psychiatry prolactinoma cabergoline impulsivity compulsive behavior case report |
| title | Binge Eating and Compulsive Buying During Cabergoline Treatment for Prolactinoma: A Case Report |
| title_full | Binge Eating and Compulsive Buying During Cabergoline Treatment for Prolactinoma: A Case Report |
| title_fullStr | Binge Eating and Compulsive Buying During Cabergoline Treatment for Prolactinoma: A Case Report |
| title_full_unstemmed | Binge Eating and Compulsive Buying During Cabergoline Treatment for Prolactinoma: A Case Report |
| title_short | Binge Eating and Compulsive Buying During Cabergoline Treatment for Prolactinoma: A Case Report |
| title_sort | binge eating and compulsive buying during cabergoline treatment for prolactinoma a case report |
| topic | prolactinoma cabergoline impulsivity compulsive behavior case report |
| url | https://www.frontiersin.org/articles/10.3389/fpsyt.2022.844718/full |
| work_keys_str_mv | AT anacarolinacorreaecastro bingeeatingandcompulsivebuyingduringcabergolinetreatmentforprolactinomaacasereport AT andressaalexandredearaujo bingeeatingandcompulsivebuyingduringcabergolinetreatmentforprolactinomaacasereport AT marianacoelhobotelho bingeeatingandcompulsivebuyingduringcabergolinetreatmentforprolactinomaacasereport AT joaobosconascimento bingeeatingandcompulsivebuyingduringcabergolinetreatmentforprolactinomaacasereport AT rafaelamarchondesouza bingeeatingandcompulsivebuyingduringcabergolinetreatmentforprolactinomaacasereport AT monicarobertogadelha bingeeatingandcompulsivebuyingduringcabergolinetreatmentforprolactinomaacasereport AT antonioenardi bingeeatingandcompulsivebuyingduringcabergolinetreatmentforprolactinomaacasereport AT alicehelenadutraviolante bingeeatingandcompulsivebuyingduringcabergolinetreatmentforprolactinomaacasereport |