Hydrophilic magnetic covalent organic frameworks for highly integrated pre-enrichment and analysis of colorectal cancer differential glycoproteomics

Finding glycoproteins related to both biomarkers and therapeutic targets is essential prerequisite. Unfortunately, the glycoproteins are hard to directly detect by mass spectrometry due to their low abundance and abundant of interferents. Herein, we report a systematic integration of enrichment and...

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Autors principals: Zhiyu Li, Yichun Gao, Peng An, Fang Lan, Yao Wu
Format: Article
Idioma:English
Publicat: Elsevier 2022-05-01
Col·lecció:Materials & Design
Matèries:
Accés en línia:http://www.sciencedirect.com/science/article/pii/S0264127522002052