Hydrophilic magnetic covalent organic frameworks for highly integrated pre-enrichment and analysis of colorectal cancer differential glycoproteomics

Finding glycoproteins related to both biomarkers and therapeutic targets is essential prerequisite. Unfortunately, the glycoproteins are hard to directly detect by mass spectrometry due to their low abundance and abundant of interferents. Herein, we report a systematic integration of enrichment and...

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Bibliographic Details
Main Authors: Zhiyu Li, Yichun Gao, Peng An, Fang Lan, Yao Wu
Format: Article
Language:English
Published: Elsevier 2022-05-01
Series:Materials & Design
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0264127522002052