Development of TaqMan probes targeting the four major celiac disease epitopes found in α-gliadin sequences of spelt (Triticum aestivum ssp. spelta) and bread wheat (Triticum aestivum ssp. aestivum)

Development of TaqMan probes targeting the four major celiac disease epitopes found in α-gliadin sequences of spelt (Triticum aestivum ssp. spelta) and bread wheat (Triticum aestivum ssp. aestivum)

Abstract Background Celiac disease (CD) is caused by specific sequences of gluten proteins found in cereals such as bread wheat (Triticum aestivum ssp. aestivum) and spelt (T. aestivum ssp. spelta). Among them, the α-gliadins display the highest immunogenicity, with four T-cell stimulatory epitopes....

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Bibliographic Details
Main Authors: Benjamin Dubois, Pierre Bertin, Yordan Muhovski, Emmanuelle Escarnot, Dominique Mingeot
Format: Article
Language:English
Published: BMC 2017-09-01
Series:Plant Methods
Subjects:
Spelt
α-gliadin
Celiac disease
TaqMan probe
Reference genes
Gluten
Online Access:http://link.springer.com/article/10.1186/s13007-017-0222-2

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http://link.springer.com/article/10.1186/s13007-017-0222-2

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