Indirect detection of an epitope-specific response to HIV-1 gp120 immunization in human subjects.
A specific response of human serum neutralizing antibodies (nAb) to a conformational epitope as a result of vaccination of human subjects with the surface envelope glycoprotein (gp120) of HIV-1 has not previously been documented. Here, we used computational analysis to assess the epitope-specific re...
Main Authors: | Evgeny Shmelkov, Arthur Nadas, James Swetnam, Susan Zolla-Pazner, Timothy Cardozo |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2011-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3208624?pdf=render |
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