Physiological level production of antigen-specific human immunoglobulin in cloned transchromosomic cattle.

Physiological level production of antigen-specific human immunoglobulin in cloned transchromosomic cattle.

Therapeutic human polyclonal antibodies (hpAbs) derived from pooled plasma from human donors are Food and Drug Administration approved biologics used in the treatment of a variety of human diseases. Powered by the natural diversity of immune response, hpAbs are effective in treating diseases caused...

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Bibliographic Details
Main Authors: Akiko Sano, Hiroaki Matsushita, Hua Wu, Jin-An Jiao, Poothappillai Kasinathan, Eddie J Sullivan, Zhongde Wang, Yoshimi Kuroiwa
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3813428?pdf=render

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