IFN-γ signaling to astrocytes protects from autoimmune mediated neurological disability.

IFN-γ signaling to astrocytes protects from autoimmune mediated neurological disability.

Demyelination and axonal degeneration are determinants of progressive neurological disability in patients with multiple sclerosis (MS). Cells resident within the central nervous system (CNS) are active participants in development, progression and subsequent control of autoimmune disease; however, th...

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Bibliographic Details
Main Authors: Claudia Hindinger, Cornelia C Bergmann, David R Hinton, Timothy W Phares, Gabriel I Parra, Shabbir Hussain, Carine Savarin, Roscoe D Atkinson, Stephen A Stohlman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22848713/?tool=EBI

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