Porcine Deltacoronavirus Utilizes Sialic Acid as an Attachment Receptor and Trypsin Can Influence the Binding Activity

Porcine Deltacoronavirus Utilizes Sialic Acid as an Attachment Receptor and Trypsin Can Influence the Binding Activity

Porcine deltacoronavirus (PDCoV) is a novel coronavirus that causes diarrhea in nursing piglets. Studies showed that PDCoV uses porcine aminopeptidase N (pAPN) as an entry receptor, but the infection of pAPN-knockout cells or pigs with PDCoV revealed that pAPN might be not a critical functional rece...

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Bibliographic Details
Main Authors: Yixin Yuan, Shaopo Zu, Yunfei Zhang, Fujie Zhao, Xiaohui Jin, Hui Hu
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Viruses
Subjects:
porcine deltacoronavirus
receptor
carbohydrates
sialic acid
trypsin
Online Access:https://www.mdpi.com/1999-4915/13/12/2442

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