Carlos Chagas Discoveries as a Drop Back to Scientific Construction of Chronic Chagas Heart Disease
Abstract The scientific construction of chronic Chagas heart disease (CCHD) started in 1910 when Carlos Chagas highlighted the presence of cardiac arrhythmia during physical examination of patients with chronic Chagas disease, and described a case of heart failure associated with myocardial inflamma...
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Sociedade Brasileira de Cardiologia (SBC)
2016-01-01
|
| Series: | Arquivos Brasileiros de Cardiologia |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0066-782X2016005015102&lng=en&tlng=en |
| _version_ | 1811253102588723200 |
|---|---|
| author | Reinaldo B. Bestetti Carolina Baraldi A. Restini Lucélio B. Couto |
| author_facet | Reinaldo B. Bestetti Carolina Baraldi A. Restini Lucélio B. Couto |
| author_sort | Reinaldo B. Bestetti |
| collection | DOAJ |
| description | Abstract The scientific construction of chronic Chagas heart disease (CCHD) started in 1910 when Carlos Chagas highlighted the presence of cardiac arrhythmia during physical examination of patients with chronic Chagas disease, and described a case of heart failure associated with myocardial inflammation and nests of parasites at autopsy. He described sudden cardiac death associated with arrhythmias in 1911, and its association with complete AV block detected by Jacquet's polygraph as Chagas reported in 1912. Chagas showed the presence of myocardial fibrosis underlying the clinical picture of CCHD in 1916, he presented a full characterization of the clinical aspects of CCHD in 1922. In 1928, Chagas detected fibrosis of the conductive system, and pointed out the presence of marked cardiomegaly at the chest X-Ray associated with minimal symptomatology. The use of serological reaction to diagnose CCHD was put into clinical practice in 1936, after Chagas' death, which along with the 12-lead ECG, revealed the epidemiological importance of CCHD in 1945. In 1953, the long period between initial infection and appearance of CCHD was established, whereas the annual incidence of CCHD from patients with the indeterminate form of the disease was established in 1956. The use of heart catheterization in 1965, exercise stress testing in 1973, Holter monitoring in 1975, Electrophysiologic testing in 1973, echocardiography in 1975, endomyocardial biopsy in 1981, and Magnetic Resonance Imaging in 1995, added to the fundamental clinical aspects of CCHD as described by Carlos Chagas. |
| first_indexed | 2024-04-12T16:44:47Z |
| format | Article |
| id | doaj.art-03a5dc5afc6c4236b1032783893213f2 |
| institution | Directory Open Access Journal |
| issn | 1678-4170 |
| language | English |
| last_indexed | 2024-04-12T16:44:47Z |
| publishDate | 2016-01-01 |
| publisher | Sociedade Brasileira de Cardiologia (SBC) |
| record_format | Article |
| series | Arquivos Brasileiros de Cardiologia |
| spelling | doaj.art-03a5dc5afc6c4236b1032783893213f22022-12-22T03:24:36ZengSociedade Brasileira de Cardiologia (SBC)Arquivos Brasileiros de Cardiologia1678-41702016-01-01010.5935/abc.20160079S0066-782X2016005015102Carlos Chagas Discoveries as a Drop Back to Scientific Construction of Chronic Chagas Heart DiseaseReinaldo B. BestettiCarolina Baraldi A. RestiniLucélio B. CoutoAbstract The scientific construction of chronic Chagas heart disease (CCHD) started in 1910 when Carlos Chagas highlighted the presence of cardiac arrhythmia during physical examination of patients with chronic Chagas disease, and described a case of heart failure associated with myocardial inflammation and nests of parasites at autopsy. He described sudden cardiac death associated with arrhythmias in 1911, and its association with complete AV block detected by Jacquet's polygraph as Chagas reported in 1912. Chagas showed the presence of myocardial fibrosis underlying the clinical picture of CCHD in 1916, he presented a full characterization of the clinical aspects of CCHD in 1922. In 1928, Chagas detected fibrosis of the conductive system, and pointed out the presence of marked cardiomegaly at the chest X-Ray associated with minimal symptomatology. The use of serological reaction to diagnose CCHD was put into clinical practice in 1936, after Chagas' death, which along with the 12-lead ECG, revealed the epidemiological importance of CCHD in 1945. In 1953, the long period between initial infection and appearance of CCHD was established, whereas the annual incidence of CCHD from patients with the indeterminate form of the disease was established in 1956. The use of heart catheterization in 1965, exercise stress testing in 1973, Holter monitoring in 1975, Electrophysiologic testing in 1973, echocardiography in 1975, endomyocardial biopsy in 1981, and Magnetic Resonance Imaging in 1995, added to the fundamental clinical aspects of CCHD as described by Carlos Chagas.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0066-782X2016005015102&lng=en&tlng=enDoença de Chagas / históriaCardiomiopatia ChagásicaArritmias CardíacasInsuficiência CardíacaCarlos Chagas |
| spellingShingle | Reinaldo B. Bestetti Carolina Baraldi A. Restini Lucélio B. Couto Carlos Chagas Discoveries as a Drop Back to Scientific Construction of Chronic Chagas Heart Disease Arquivos Brasileiros de Cardiologia Doença de Chagas / história Cardiomiopatia Chagásica Arritmias Cardíacas Insuficiência Cardíaca Carlos Chagas |
| title | Carlos Chagas Discoveries as a Drop Back to Scientific Construction of Chronic Chagas Heart Disease |
| title_full | Carlos Chagas Discoveries as a Drop Back to Scientific Construction of Chronic Chagas Heart Disease |
| title_fullStr | Carlos Chagas Discoveries as a Drop Back to Scientific Construction of Chronic Chagas Heart Disease |
| title_full_unstemmed | Carlos Chagas Discoveries as a Drop Back to Scientific Construction of Chronic Chagas Heart Disease |
| title_short | Carlos Chagas Discoveries as a Drop Back to Scientific Construction of Chronic Chagas Heart Disease |
| title_sort | carlos chagas discoveries as a drop back to scientific construction of chronic chagas heart disease |
| topic | Doença de Chagas / história Cardiomiopatia Chagásica Arritmias Cardíacas Insuficiência Cardíaca Carlos Chagas |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0066-782X2016005015102&lng=en&tlng=en |
| work_keys_str_mv | AT reinaldobbestetti carloschagasdiscoveriesasadropbacktoscientificconstructionofchronicchagasheartdisease AT carolinabaraldiarestini carloschagasdiscoveriesasadropbacktoscientificconstructionofchronicchagasheartdisease AT luceliobcouto carloschagasdiscoveriesasadropbacktoscientificconstructionofchronicchagasheartdisease |