Current Research and Development of Chemotherapeutic Agents for Melanoma
Cutaneous malignant melanoma is the most lethal form of skin cancer and an increasingly common disease worldwide. It remains one of the most treatment-refractory malignancies. The current treatment options for patients with metastatic melanoma are limited and in most cases non-curative. This review...
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| Format: | Article |
| Language: | English |
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MDPI AG
2010-04-01
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| Series: | Cancers |
| Subjects: | |
| Online Access: | http://www.mdpi.com/2072-6694/2/2/397/ |
| _version_ | 1797762233036439552 |
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| author | Kyaw Minn Hsan Chun-Chieh Chen Lie-Fen Shyur |
| author_facet | Kyaw Minn Hsan Chun-Chieh Chen Lie-Fen Shyur |
| author_sort | Kyaw Minn Hsan |
| collection | DOAJ |
| description | Cutaneous malignant melanoma is the most lethal form of skin cancer and an increasingly common disease worldwide. It remains one of the most treatment-refractory malignancies. The current treatment options for patients with metastatic melanoma are limited and in most cases non-curative. This review focuses on conventional chemotherapeutic drugs for melanoma treatment, by a single or combinational agent approach, but also summarizes some potential novel phytoagents discovered from dietary vegetables or traditional herbal medicines as alternative options or future medicine for melanoma prevention. We explore the mode of actions of these natural phytoagents against metastatic melanoma. |
| first_indexed | 2024-03-12T19:24:23Z |
| format | Article |
| id | doaj.art-03abd842fdb04f59bf201791def15da9 |
| institution | Directory Open Access Journal |
| issn | 2072-6694 |
| language | English |
| last_indexed | 2024-03-12T19:24:23Z |
| publishDate | 2010-04-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Cancers |
| spelling | doaj.art-03abd842fdb04f59bf201791def15da92023-08-02T04:55:47ZengMDPI AGCancers2072-66942010-04-012239741910.3390/cancers2020397Current Research and Development of Chemotherapeutic Agents for MelanomaKyaw Minn HsanChun-Chieh ChenLie-Fen ShyurCutaneous malignant melanoma is the most lethal form of skin cancer and an increasingly common disease worldwide. It remains one of the most treatment-refractory malignancies. The current treatment options for patients with metastatic melanoma are limited and in most cases non-curative. This review focuses on conventional chemotherapeutic drugs for melanoma treatment, by a single or combinational agent approach, but also summarizes some potential novel phytoagents discovered from dietary vegetables or traditional herbal medicines as alternative options or future medicine for melanoma prevention. We explore the mode of actions of these natural phytoagents against metastatic melanoma.http://www.mdpi.com/2072-6694/2/2/397/cutaneous malignant melanomametastasischemotherapeutic drugsherbal medicinesphytoagents |
| spellingShingle | Kyaw Minn Hsan Chun-Chieh Chen Lie-Fen Shyur Current Research and Development of Chemotherapeutic Agents for Melanoma Cancers cutaneous malignant melanoma metastasis chemotherapeutic drugs herbal medicines phytoagents |
| title | Current Research and Development of Chemotherapeutic Agents for Melanoma |
| title_full | Current Research and Development of Chemotherapeutic Agents for Melanoma |
| title_fullStr | Current Research and Development of Chemotherapeutic Agents for Melanoma |
| title_full_unstemmed | Current Research and Development of Chemotherapeutic Agents for Melanoma |
| title_short | Current Research and Development of Chemotherapeutic Agents for Melanoma |
| title_sort | current research and development of chemotherapeutic agents for melanoma |
| topic | cutaneous malignant melanoma metastasis chemotherapeutic drugs herbal medicines phytoagents |
| url | http://www.mdpi.com/2072-6694/2/2/397/ |
| work_keys_str_mv | AT kyawminnhsan currentresearchanddevelopmentofchemotherapeuticagentsformelanoma AT chunchiehchen currentresearchanddevelopmentofchemotherapeuticagentsformelanoma AT liefenshyur currentresearchanddevelopmentofchemotherapeuticagentsformelanoma |