Nk3R blockade has sex-divergent effects on memory in mice

Highlights Nk3R antagonism reduces recognition memory consolidation in male mice and increases it in proestrus females. Androgen receptor expression is higher in the CA1 compared to DG, CA3, and the mPFC. Estrogen repcetor α expression is higher in males than in females in the DH and mPFC. Estrogen...

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Bibliographic Details
Main Authors: Antonio Florido, Estefanía Moreno, Enric I. Canela, Raül Andero
Format: Article
Language:English
Published: BMC 2022-06-01
Series:Biology of Sex Differences
Subjects:
Online Access:https://doi.org/10.1186/s13293-022-00437-z