Cadherin-13 Deficiency Increases Dorsal Raphe 5-HT Neuron Density and Prefrontal Cortex Innervation in the Mouse Brain

Cadherin-13 Deficiency Increases Dorsal Raphe 5-HT Neuron Density and Prefrontal Cortex Innervation in the Mouse Brain

Background: During early prenatal stages of brain development, serotonin (5-HT)-specific neurons migrate through somal translocation to form the raphe nuclei and subsequently begin to project to their target regions. The rostral cluster of cells, comprising the median and dorsal raphe (DR), innervat...

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Bibliographic Details
Main Authors: Andrea Forero, Olga Rivero, Sina Wäldchen, Hsing-Ping Ku, Dominik P. Kiser, Yvonne Gärtner, Laura S. Pennington, Jonas Waider, Patricia Gaspar, Charline Jansch, Frank Edenhofer, Thérèse J. Resink, Robert Blum, Markus Sauer, Klaus-Peter Lesch
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-09-01
Series:Frontiers in Cellular Neuroscience
Subjects:
serotonin
cadherin-13 (CDH13)
T-cadherin
neurodevelopment
psychiatric disorders
radial glia
Online Access:http://journal.frontiersin.org/article/10.3389/fncel.2017.00307/full

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