Development of Cobalt-Binding Peptide Chelate from Human Serum Albumin: Cobalt-Binding Properties and Stability

Development of Cobalt-Binding Peptide Chelate from Human Serum Albumin: Cobalt-Binding Properties and Stability

Radioactive isotopes are used as drugs or contrast agents in the medical field after being conjugated with chelates such as DOTA, NOTA, DTPA, TETA, CyDTA, TRITA, and DPDP. The N-terminal sequence of human serum albumin (HSA) is known as a metal binding site, such as for Co<sup>2+</sup>,...

Full description

Bibliographic Details
Main Authors: Yeonje Cho, Armin Mirzapour-Kouhdasht, Hyosuk Yun, Jeong Hoon Park, Hye Jung Min, Chul Won Lee
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:International Journal of Molecular Sciences
Subjects:
peptides
cobalt binding
structure
stability
Online Access:https://www.mdpi.com/1422-0067/23/2/719

Similar Items

Similar Items