Colorectal cancer with peritoneal carcinomatosis in a teenager

Colorectal cancer is a rare disease in children. It is often diagnosed at an advanced stage, meaning that these patients often require a multidisciplinary treatment approach. This is a case report of advanced cecal cancer in a teenager who was treated with cytoreductive surgery and long-term chemoth...

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Main Authors: Shuji Nakamoto, Kiyoshi Tanaka, Eiichiro Watanabe, Noriko Takeda, Takatoshi Nakamura, Yusuke Kumamoto
Format: Article
Language:English
Published: Elsevier 2020-03-01
Series:Journal of Pediatric Surgery Case Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2213576619303793
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author Shuji Nakamoto
Kiyoshi Tanaka
Eiichiro Watanabe
Noriko Takeda
Takatoshi Nakamura
Yusuke Kumamoto
author_facet Shuji Nakamoto
Kiyoshi Tanaka
Eiichiro Watanabe
Noriko Takeda
Takatoshi Nakamura
Yusuke Kumamoto
author_sort Shuji Nakamoto
collection DOAJ
description Colorectal cancer is a rare disease in children. It is often diagnosed at an advanced stage, meaning that these patients often require a multidisciplinary treatment approach. This is a case report of advanced cecal cancer in a teenager who was treated with cytoreductive surgery and long-term chemotherapy with molecular targeted agents.A previously healthy 15-year-old boy was referred to our hospital with a two-month history of abdominal pain and diarrhea. On physical examination, his abdomen was distended and a tender mass was palpable in the right lower quadrant. Laboratory data revealed severe anemia and elevated tumor markers. Computed tomography showed thickening of the cecal wall and multiple peritoneal nodules. He was diagnosed with advanced cecal cancer with peritoneal metastasis, and underwent right colectomy, followed by 5-fluorouracil-based chemotherapy with molecular targeted agents. However, his disease continued to progress, and the patient died 17 months after his initial diagnosis.The rarity of this disease means diagnosis is difficult and that there is little evidence on best treatment; therefore, more research is needed in these areas. Keywords: Colorectal cancer, Peritoneal carcinomatosis, Pediatrics
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spelling doaj.art-03b873b4f4f84a188789b57a5a463c1f2022-12-22T00:51:04ZengElsevierJournal of Pediatric Surgery Case Reports2213-57662020-03-0154Colorectal cancer with peritoneal carcinomatosis in a teenagerShuji Nakamoto0Kiyoshi Tanaka1Eiichiro Watanabe2Noriko Takeda3Takatoshi Nakamura4Yusuke Kumamoto5Department of Surgery, Kitasato University Hospital, Kitasato 1-15-1, Minami-ku, Sagamihara, Kanagawa, 252-0374, JapanDepartment of Pediatric Surgery, Kitasato University Hospital, Kitasato 1-15-1, Minami-ku, Sagamihara, Kanagawa, 252-0374, Japan; Division of Pediatric Surgery, Research and Development Center for New Medical Frontiers, Kitasato University School of Medicine, Kitasato 1-15-1, Minami-ku, Sagamihara, Kanagawa, 252-0374, Japan; Corresponding authorDivision of Pediatric Surgery, Research and Development Center for New Medical Frontiers, Kitasato University School of Medicine, Kitasato 1-15-1, Minami-ku, Sagamihara, Kanagawa, 252-0374, Japan.Department of Pediatric Surgery, Kitasato University Hospital, Kitasato 1-15-1, Minami-ku, Sagamihara, Kanagawa, 252-0374, JapanDepartment of Pediatric Surgery, Kitasato University Hospital, Kitasato 1-15-1, Minami-ku, Sagamihara, Kanagawa, 252-0374, JapanDepartment of Surgery, Kitasato University Hospital, Kitasato 1-15-1, Minami-ku, Sagamihara, Kanagawa, 252-0374, JapanDepartment of Surgery, Kitasato University Hospital, Kitasato 1-15-1, Minami-ku, Sagamihara, Kanagawa, 252-0374, JapanColorectal cancer is a rare disease in children. It is often diagnosed at an advanced stage, meaning that these patients often require a multidisciplinary treatment approach. This is a case report of advanced cecal cancer in a teenager who was treated with cytoreductive surgery and long-term chemotherapy with molecular targeted agents.A previously healthy 15-year-old boy was referred to our hospital with a two-month history of abdominal pain and diarrhea. On physical examination, his abdomen was distended and a tender mass was palpable in the right lower quadrant. Laboratory data revealed severe anemia and elevated tumor markers. Computed tomography showed thickening of the cecal wall and multiple peritoneal nodules. He was diagnosed with advanced cecal cancer with peritoneal metastasis, and underwent right colectomy, followed by 5-fluorouracil-based chemotherapy with molecular targeted agents. However, his disease continued to progress, and the patient died 17 months after his initial diagnosis.The rarity of this disease means diagnosis is difficult and that there is little evidence on best treatment; therefore, more research is needed in these areas. Keywords: Colorectal cancer, Peritoneal carcinomatosis, Pediatricshttp://www.sciencedirect.com/science/article/pii/S2213576619303793
spellingShingle Shuji Nakamoto
Kiyoshi Tanaka
Eiichiro Watanabe
Noriko Takeda
Takatoshi Nakamura
Yusuke Kumamoto
Colorectal cancer with peritoneal carcinomatosis in a teenager
Journal of Pediatric Surgery Case Reports
title Colorectal cancer with peritoneal carcinomatosis in a teenager
title_full Colorectal cancer with peritoneal carcinomatosis in a teenager
title_fullStr Colorectal cancer with peritoneal carcinomatosis in a teenager
title_full_unstemmed Colorectal cancer with peritoneal carcinomatosis in a teenager
title_short Colorectal cancer with peritoneal carcinomatosis in a teenager
title_sort colorectal cancer with peritoneal carcinomatosis in a teenager
url http://www.sciencedirect.com/science/article/pii/S2213576619303793
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