The Effects of Chemotherapeutics on the Ovarian Cancer Microenvironment

The Effects of Chemotherapeutics on the Ovarian Cancer Microenvironment

High-grade serous ovarian cancer (HGSOC) is characterized by a complex and dynamic tumor microenvironment (TME) composed of cancer-associated fibroblasts (CAFs), immune cells, endothelial cells, and adipocytes. Although most approved therapies target cancer cells, a growing body of evidence suggests...

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Bibliographic Details
Main Authors: Mark A. Eckert, Carlos Orozco, Jason Xiao, Melissa Javellana, Ernst Lengyel
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Cancers
Subjects:
tumor microenvironment
stroma
cancer-associated fibroblasts
ovarian cancer
cancer therapy
carboplatin
Online Access:https://www.mdpi.com/2072-6694/13/13/3136

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