Gut Microbiota-Derived Indole-3-Carboxylate Influences Mucosal Integrity and Immunity Through the Activation of the Aryl Hydrocarbon Receptors and Nutrient Transporters in Broiler Chickens Challenged With Eimeria maxima

Gut Microbiota-Derived Indole-3-Carboxylate Influences Mucosal Integrity and Immunity Through the Activation of the Aryl Hydrocarbon Receptors and Nutrient Transporters in Broiler Chickens Challenged With Eimeria maxima

Two studies were conducted to evaluate the effects of indole-3-carboxylate (ICOOH) as a postbiotic on maintaining intestinal homeostasis against avian coccidiosis. In the first study, an in vitro culture system was used to investigate the effects of ICOOH on the proinflammatory cytokine response of...

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Bibliographic Details
Main Authors: Inkyung Park, Hyoyoun Nam, Doyun Goo, Samiru S. Wickramasuriya, Noah Zimmerman, Alexandra H. Smith, Thomas G. Rehberger, Hyun S. Lillehoj
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Immunology
Subjects:
broiler chickens
Eimeria maxima
indole-3-carboxylate
intestinal immunity
gut health
microbial metabolites
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.867754/full

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