Propofol inhibits neuroinflammation and metabolic reprogramming in microglia in vitro and in vivo
Microglial activation-induced neuroinflammation is closely related to the development of sepsis-associated encephalopathy. Accumulating evidence suggests that changes in the metabolic profile of microglia is crucial for their response to inflammation. Propofol is widely used for sedation in mechanic...
Main Authors: | Shuyuan Guan, Lingbin Sun, Xihua Wang, Xirui Huang, Tao Luo |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2023-06-01
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Series: | Frontiers in Pharmacology |
Subjects: | |
Online Access: | https://www.frontiersin.org/articles/10.3389/fphar.2023.1161810/full |
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