The Incidence of Renal Cell Carcinoma Is Increased in Patients With Obstructive Sleep Apnea

Background and Objective Many studies have indicated that obstructive sleep apnea (OSA) is linked to the development of cancer. However, there have been few studies about the link between OSA and renal cell carcinoma (RCC). This study investigated the relationship between OSA and RCC by analyzing th...

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Main Authors: Hyoung Keun Park, Woo Suk Choi, Jae Hoon Cho
Format: Article
Language:English
Published: Korean Society of Sleep Medicine 2022-09-01
Series:Sleep Medicine Research
Subjects:
Online Access:http://www.sleepmedres.org/upload/pdf/smr-2022-01305.pdf
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author Hyoung Keun Park
Woo Suk Choi
Jae Hoon Cho
author_facet Hyoung Keun Park
Woo Suk Choi
Jae Hoon Cho
author_sort Hyoung Keun Park
collection DOAJ
description Background and Objective Many studies have indicated that obstructive sleep apnea (OSA) is linked to the development of cancer. However, there have been few studies about the link between OSA and renal cell carcinoma (RCC). This study investigated the relationship between OSA and RCC by analyzing the data from the Korea National Health Insurance Service. Methods 198574 patients (≥ 20 years of age) newly diagnosed with OSA from 2007 to 2014 were included and 992870 control groups were selected through propensity score matching according to sex and age. The average follow-up period was 4.6 years. The primary outcome was newly diagnosed RCC. The hazard ratio for RCC in patients with OSA was compared to that in the control group. Results The incidence of RCC was significantly higher among patients with OSA than among controls (hazard ratio, 1.65; 95% confidence interval, 1.41–1.93). Conclusions OSA may be a potential risk factor for RCC.
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spelling doaj.art-03c654c5aae845ad8f0d7af2ca5b4e812022-12-22T02:31:57ZengKorean Society of Sleep MedicineSleep Medicine Research2093-91752233-88532022-09-01132818410.17241/smr.2022.01305207The Incidence of Renal Cell Carcinoma Is Increased in Patients With Obstructive Sleep ApneaHyoung Keun Park0Woo Suk Choi1Jae Hoon Cho2 Department of Urology, Konkuk University School of Medicine, Seoul, Korea Department of Urology, Konkuk University School of Medicine, Seoul, Korea Department of Otorhinolaryngology-Head and Neck Surgery, Konkuk University School of Medicine, Seoul, KoreaBackground and Objective Many studies have indicated that obstructive sleep apnea (OSA) is linked to the development of cancer. However, there have been few studies about the link between OSA and renal cell carcinoma (RCC). This study investigated the relationship between OSA and RCC by analyzing the data from the Korea National Health Insurance Service. Methods 198574 patients (≥ 20 years of age) newly diagnosed with OSA from 2007 to 2014 were included and 992870 control groups were selected through propensity score matching according to sex and age. The average follow-up period was 4.6 years. The primary outcome was newly diagnosed RCC. The hazard ratio for RCC in patients with OSA was compared to that in the control group. Results The incidence of RCC was significantly higher among patients with OSA than among controls (hazard ratio, 1.65; 95% confidence interval, 1.41–1.93). Conclusions OSA may be a potential risk factor for RCC.http://www.sleepmedres.org/upload/pdf/smr-2022-01305.pdfobstructive sleep apnearenal cell carcinomaincidencecancerrisk factor
spellingShingle Hyoung Keun Park
Woo Suk Choi
Jae Hoon Cho
The Incidence of Renal Cell Carcinoma Is Increased in Patients With Obstructive Sleep Apnea
Sleep Medicine Research
obstructive sleep apnea
renal cell carcinoma
incidence
cancer
risk factor
title The Incidence of Renal Cell Carcinoma Is Increased in Patients With Obstructive Sleep Apnea
title_full The Incidence of Renal Cell Carcinoma Is Increased in Patients With Obstructive Sleep Apnea
title_fullStr The Incidence of Renal Cell Carcinoma Is Increased in Patients With Obstructive Sleep Apnea
title_full_unstemmed The Incidence of Renal Cell Carcinoma Is Increased in Patients With Obstructive Sleep Apnea
title_short The Incidence of Renal Cell Carcinoma Is Increased in Patients With Obstructive Sleep Apnea
title_sort incidence of renal cell carcinoma is increased in patients with obstructive sleep apnea
topic obstructive sleep apnea
renal cell carcinoma
incidence
cancer
risk factor
url http://www.sleepmedres.org/upload/pdf/smr-2022-01305.pdf
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