Metabolomics study of treatment response to conbercept of patients with neovascular age-related macular degeneration and polypoidal choroidal vasculopathy

Metabolomics study of treatment response to conbercept of patients with neovascular age-related macular degeneration and polypoidal choroidal vasculopathy

Graphical AbstractAMD, age-related macular degeneration; PCV, polypoidal choroidal vasculopathy; PLS-DA, partial least squares discriminant analysis; LPC, lysophosphatidylcholine; PC, phosphocholine; ROC, operating characteristic curve; AUC, area under the receiver operating characteristic curve; vW...

Full description

Bibliographic Details
Main Authors:	Yinchen Shen, Hanying Wang, Xiaoyin Xu, Chong Chen, Shaopin Zhu, Lu Cheng, Junwei Fang, Kun Liu, Xun Xu
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2022-09-01
Series:	Frontiers in Pharmacology
Subjects:	anti-vegf neovascular age-related macular degeneration polypoidal choroidal vasculopathy metabolomics treatment response
Online Access:	https://www.frontiersin.org/articles/10.3389/fphar.2022.991879/full

Similar Items

Novel insights into the mechanisms of hard exudate in diabetic retinopathy: Findings of serum lipidomic and metabolomics profiling
by: Yinchen Shen, et al.
Published: (2023-04-01)

Anti-scarring effects of conbercept on human Tenon’s fibroblasts: comparisons with bevacizumab
by: Lei Zuo, et al.
Published: (2023-04-01)

Observation of a pulsatile choroidal vascular lesion in a patient with polypoidal choroid vasculopathy during vitrectomy
by: Ting Zhang, et al.
Published: (2022-06-01)

Eplerenone in the Treatment of Polypoidal Choroidal Vasculopathy
by: Kapil G. Kapoor, et al.
Published: (2015-12-01)

Different Morphology of Branching Neovascular Network in Polypoidal Choroidal Vasculopathy: A Swept-Source Optical Coherence Tomography Angiography Study
by: Lulu Chen, et al.
Published: (2023-01-01)

Systemic Risk Factors for Vitreous Hemorrhage Secondary to Polypoidal Choroidal Vasculopathy
by: Baoyi Liu, et al.
Published: (2023-08-01)

Characteristics of Fundus Autofluorescence in Active Polypoidal Choroidal Vasculopathy
by: Zafer Öztaş, et al.
Published: (2016-08-01)

Analysis of Systemic and Serum Risk Factors in Patients with Age-Related Macular Degeneration and Polypoidal Choroidal Vasculopathy
by: Tianchang Tao, et al.
Published: (2023-01-01)

Treatment Outcomes in Patients with Polypoidal Choroidal Vasculopathy
by: Mümin Hocaoğlu, et al.
Published: (2016-01-01)

Comparison of Two-Year Outcome of Photodynamic Therapy in Combination with Intravitreal Aflibercept or Ranibizumab for Polypoidal Choroidal Vasculopathy
by: Hsin-Yu Weng, et al.
Published: (2021-01-01)

Occurrence of circumscribed choroidal hemangioma accompanied by polypoidal choroidal vasculopathy and branch retinal vein occlusion: a case report
by: Qin Zhang, et al.
Published: (2023-04-01)

Comparison of Outcomes between 3 Monthly Brolucizumab and Aflibercept Injections for Polypoidal Choroidal Vasculopathy
by: Yoshiko Fukuda, et al.
Published: (2021-09-01)

Photodynamic Therapy and Bevacizumab Combination for Polypoidal Choroidal Vasculopathy Refractory to Intravitreal Ranibizumab
by: Zeynep Alkin, et al.
Published: (2016-12-01)

Initial experience in treating polypoidal choroidal vasculopathy with brolucizumab in Indian eyes – A multicenter retrospective study
by: DebdulalChakraborty, et al.
Published: (2022-01-01)

Long-term observation of vitrectomy without subretinal hemorrhage management for massive vitreous hemorrhage secondary to polypoidal choroidal vasculopathy
by: Zhi-Xi Li, et al.
Published: (2019-12-01)

Effect of Epiretinal Membrane Peeling on Intravitreal Aflibercept Therapy Response for Polypoidal Choroidal Vasculopathy: A Case Report
by: Aslı Kırmacı, et al.
Published: (2018-04-01)

Advances in multi-modal non-invasive imaging techniques in the diagnosis and treatment of polypoidal choroidal vasculopathy
by: Yuelin Wang, et al.
Published: (2023-07-01)

AFLIBERCEPT IN TREATMENT OF RESISTANT POLYPOID CHOROIDAL VASCULOPATHY: SHORT-TERM RESULTS
by: E. K. Pedanova, et al.
Published: (2017-12-01)

Polypoidal Choroidal Vasculopathy: An Update on Therapeutic Approaches
by: Raymond L.M. Wong, et al.
Published: (2013-01-01)

Short-Term Outcomes of Switching to Ranibizumab in Polypoidal Choroidal Vasculopathy Resistant to Aflibercept Therapy
by: Young-Joon Jeon, et al.
Published: (2021-12-01)

One-year real-world outcomes of ranibizumab 0.5 mg treatment in Taiwanese patients with polypoidal choroidal vasculopathy: a subgroup analysis of the REAL study
by: San-Ni Chen, et al.
Published: (2018-11-01)

Plasma Levels of Matrix Metalloprotease MMP-9 and Tissue Inhibitor TIMP-1 in Caucasian Patients with Polypoidal Choroidal Vasculopathy
by: Jakob Ø. Sørensen, et al.
Published: (2020-05-01)

Two-Year Results of Photodynamic Therapy Combined with Intravitreal Anti-Vascular Endothelial Growth Factor for Polypoidal Choroidal Vasculopathy; A Real Life Experience
by: Sibel Ahmet, et al.
Published: (2017-12-01)

Enhancement of glycolysis-dependent DNA repair regulated by FOXO1 knockdown via PFKFB3 attenuates hyperglycemia-induced endothelial oxidative stress injury
by: Dandan Sun, et al.
Published: (2023-02-01)

Updated guidelines for the management of polypoidal choroidal vasculopathy: Recommendations from the Indian Polypoidal Choroidal Vasculopathy Panel and the Vitreoretinal Society of India
by: Jay U Sheth, et al.
Published: (2022-01-01)

Pachydrusen in Fellow Eyes Predict Response to Aflibercept Monotherapy in Patients with Polypoidal Choroidal Vasculopathy
by: Yoshiko Fukuda, et al.
Published: (2020-07-01)

Quantitative evaluation of ocular vascularity and correlation analysis in patients with diabetic retinopathy by SMI and OCTA
by: Jin Wei, et al.
Published: (2024-02-01)

The Association of Pachydrusen Characteristics with Choroidal Thickness and Patient’s Age in Polypoidal Choroidal Vasculopathy versus Central Serous Chorioretinopathy
by: Young Ho Kim, et al.
Published: (2022-07-01)

Polypoidal choroidal vasculopathy mimicking as central serous chorioretinopathy
by: Preeti Surpur, et al.
Published: (2023-01-01)

CURRENT ASPECTS OF DIAGNOSIS AND TREATMENT OF POLYPOIDAL CHOROIDAL VASCULOPATHY
by: A. V. Doga, et al.
Published: (2017-04-01)

Current management strategy of polypoidal choroidal vasculopathy
by: Christine P S Ho, et al.
Published: (2018-01-01)

Seven-year outcomes of combined treatment of anti-vascular endothelial growth factor with photodynamic therapy for polypoidal choroidal vasculopathy; according to polypoidal lesion regression
by: Junwoo Lee, et al.
Published: (2023-12-01)

Ethnic differences on long term outcomes of polypoidal choroidal vasculopathy after predominantly bevacizumab monotherapy
by: Aaron Yap, et al.
Published: (2022-07-01)

Association between inflammatory cytokines in the aqueous humor and hyperreflective foci on optical coherence tomography in patients with neovascular age-related macular degeneration and polypoidal choroidal vasculopathy
by: Jianbo Mao, et al.
Published: (2022-09-01)

Recent Advances in Imaging Polypoidal Choroidal Vasculopathy with Swept-Source Optical Coherence Tomography Angiography
by: Xingwang Gu, et al.
Published: (2023-07-01)

Six-Year Outcomes in Subjects with Polypoidal Choroidal Vasculopathy in the EVEREST II Study
by: Kelvin Yi Chong Teo, et al.
Published: (2024-02-01)

European Prevalence of Polypoidal Choroidal Vasculopathy: A Systematic Review, Meta-Analysis, and Forecasting Study
by: Elon H. C. van Dijk, et al.
Published: (2022-08-01)

Comparison of the 2-Year Results of Photodynamic Therapy with Aflibercept and Aflibercept Monotherapy for Polypoidal Choroidal Vasculopathy
by: Miyakubo T, et al.
Published: (2023-02-01)

Relationship between Pachychoroid and Polypoidal Choroidal Vasculopathy
by: Kenji Yamashiro, et al.
Published: (2022-08-01)

Prevalence of Polypoidal Choroidal Vasculopathy in Eyes with Neovascular Age-Related Macular Degeneration Resistant to Intravitreal Anti-VEGF Treatment
by: Jale Menteş, et al.
Published: (2022-10-01)