CD8 T-cell subsets: heterogeneity, functions, and therapeutic potential

Abstract CD8 T cells play crucial roles in immune surveillance and defense against infections and cancer. After encountering antigenic stimulation, naïve CD8 T cells differentiate and acquire effector functions, enabling them to eliminate infected or malignant cells. Traditionally, cytotoxic T cells...

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Bibliographic Details
Main Authors: Choong-Hyun Koh, Suyoung Lee, Minkyeong Kwak, Byung-Seok Kim, Yeonseok Chung
Format: Article
Language:English
Published: Nature Publishing Group 2023-11-01
Series:Experimental and Molecular Medicine
Online Access:https://doi.org/10.1038/s12276-023-01105-x