Crossing design shapes patterns of genetic variation in synthetic recombinant populations of Saccharomyces cerevisiae

Abstract “Synthetic recombinant” populations have emerged as a useful tool for dissecting the genetics of complex traits. They can be used to derive inbred lines for fine QTL mapping, or the populations themselves can be sampled for experimental evolution. In the latter application, investigators ge...

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Bibliographic Details
Main Authors: Mark A. Phillips, Ian C. Kutch, Kaitlin M. McHugh, Savannah K. Taggard, Molly K. Burke
Format: Article
Language:English
Published: Nature Portfolio 2021-10-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-99026-0