RARE BENIGN EYELID TUMOR IN CHILDREN (EPITHELIOMA OF MALHERBE, PILOMATRIXOMA, OR TRICHELEMMOMA)
Aim. To describe clinical manifestations of rare eyelid tumor (epithelioma Malherbe) and to improve differential diagnosis of benign eyelid tumors in children. Patients and methods. We observed 8 children aged 3,5‑8 years (sex ratio was 1:1). In all cases, examination, palpation, surgical excision o...
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| Format: | Article |
| Language: | Russian |
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Ophthalmology Publishing Group
2015-07-01
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| Series: | Oftalʹmologiâ |
| Subjects: | |
| Online Access: | https://www.ophthalmojournal.com/opht/article/view/249 |
| _version_ | 1797875493907726336 |
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| author | A. A. Ryabtseva V. Yu. Kokorev S. V. Tarannikova |
| author_facet | A. A. Ryabtseva V. Yu. Kokorev S. V. Tarannikova |
| author_sort | A. A. Ryabtseva |
| collection | DOAJ |
| description | Aim. To describe clinical manifestations of rare eyelid tumor (epithelioma Malherbe) and to improve differential diagnosis of benign eyelid tumors in children. Patients and methods. We observed 8 children aged 3,5‑8 years (sex ratio was 1:1). In all cases, examination, palpation, surgical excision of the tumor with histological examination were performed. Results. Trichilemmoma, or pilomatricoma, was suggested from clinical manifestations. Epithelioma Malherbe was diagnosed by histology only. Microscopically, the tumor is surrounded by a capsule which includes two cell types. Peripheral basophilic cells are small cells with poor cytoplasm, indistinct borders, and deeply basophilic nucleus. Central shadow cells have a distinct border and a central unstained area. Islands of small basaloid epithelial cells with squamous cell focuses and cornification are embedded in the stroma. Epithelial lesions are often necrotized. Epithelial mass is surrounded by granulations with giant cells. Osseous trabeculae are often adjacent to necrotic lesions. Further follow-up revealed no complications or recurrences. Conclusions. Our observations and literature data suggest that epithelioma Malherbe is occured in 1.3 % of benign eyelid tumors in childern. Tumor growth is slow and non-invasive. |
| first_indexed | 2024-04-10T01:48:26Z |
| format | Article |
| id | doaj.art-03ccbf4c55164d1789fe742a5b1329d6 |
| institution | Directory Open Access Journal |
| issn | 1816-5095 2500-0845 |
| language | Russian |
| last_indexed | 2024-04-10T01:48:26Z |
| publishDate | 2015-07-01 |
| publisher | Ophthalmology Publishing Group |
| record_format | Article |
| series | Oftalʹmologiâ |
| spelling | doaj.art-03ccbf4c55164d1789fe742a5b1329d62023-03-13T09:08:36ZrusOphthalmology Publishing GroupOftalʹmologiâ1816-50952500-08452015-07-01122889210.18008/1816-5095-2015-2-88-92244RARE BENIGN EYELID TUMOR IN CHILDREN (EPITHELIOMA OF MALHERBE, PILOMATRIXOMA, OR TRICHELEMMOMA)A. A. Ryabtseva0V. Yu. Kokorev1S. V. Tarannikova2Московский областной научно-исследовательский клинический институт им. М. Ф. ВладимирскогоМосковский областной научно-исследовательский клинический институт им. М. Ф. ВладимирскогоМосковский областной научно-исследовательский клинический институт им. М. Ф. ВладимирскогоAim. To describe clinical manifestations of rare eyelid tumor (epithelioma Malherbe) and to improve differential diagnosis of benign eyelid tumors in children. Patients and methods. We observed 8 children aged 3,5‑8 years (sex ratio was 1:1). In all cases, examination, palpation, surgical excision of the tumor with histological examination were performed. Results. Trichilemmoma, or pilomatricoma, was suggested from clinical manifestations. Epithelioma Malherbe was diagnosed by histology only. Microscopically, the tumor is surrounded by a capsule which includes two cell types. Peripheral basophilic cells are small cells with poor cytoplasm, indistinct borders, and deeply basophilic nucleus. Central shadow cells have a distinct border and a central unstained area. Islands of small basaloid epithelial cells with squamous cell focuses and cornification are embedded in the stroma. Epithelial lesions are often necrotized. Epithelial mass is surrounded by granulations with giant cells. Osseous trabeculae are often adjacent to necrotic lesions. Further follow-up revealed no complications or recurrences. Conclusions. Our observations and literature data suggest that epithelioma Malherbe is occured in 1.3 % of benign eyelid tumors in childern. Tumor growth is slow and non-invasive.https://www.ophthalmojournal.com/opht/article/view/249доброкачественные новообразования векэпителиома малербапиломатриксомагистологическое исследованиеволосяной фолликулоперативное лечение |
| spellingShingle | A. A. Ryabtseva V. Yu. Kokorev S. V. Tarannikova RARE BENIGN EYELID TUMOR IN CHILDREN (EPITHELIOMA OF MALHERBE, PILOMATRIXOMA, OR TRICHELEMMOMA) Oftalʹmologiâ доброкачественные новообразования век эпителиома малерба пиломатриксома гистологическое исследование волосяной фолликул оперативное лечение |
| title | RARE BENIGN EYELID TUMOR IN CHILDREN (EPITHELIOMA OF MALHERBE, PILOMATRIXOMA, OR TRICHELEMMOMA) |
| title_full | RARE BENIGN EYELID TUMOR IN CHILDREN (EPITHELIOMA OF MALHERBE, PILOMATRIXOMA, OR TRICHELEMMOMA) |
| title_fullStr | RARE BENIGN EYELID TUMOR IN CHILDREN (EPITHELIOMA OF MALHERBE, PILOMATRIXOMA, OR TRICHELEMMOMA) |
| title_full_unstemmed | RARE BENIGN EYELID TUMOR IN CHILDREN (EPITHELIOMA OF MALHERBE, PILOMATRIXOMA, OR TRICHELEMMOMA) |
| title_short | RARE BENIGN EYELID TUMOR IN CHILDREN (EPITHELIOMA OF MALHERBE, PILOMATRIXOMA, OR TRICHELEMMOMA) |
| title_sort | rare benign eyelid tumor in children epithelioma of malherbe pilomatrixoma or trichelemmoma |
| topic | доброкачественные новообразования век эпителиома малерба пиломатриксома гистологическое исследование волосяной фолликул оперативное лечение |
| url | https://www.ophthalmojournal.com/opht/article/view/249 |
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