MMP-15 is upregulated in preeclampsia, but does not cleave endoglin to produce soluble endoglin.

MMP-15 is upregulated in preeclampsia, but does not cleave endoglin to produce soluble endoglin.

Preeclampsia is a major pregnancy complication, characterized by severe endothelial dysfunction, hypertension and maternal end-organ damage. Soluble endoglin is an anti-angiogenic protein released from placenta and thought to play a central role in causing the endothelial dysfunction and maternal or...

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Bibliographic Details
Main Authors: Tu'uhevaha J Kaitu'u-Lino, Kirsten Palmer, Laura Tuohey, Louie Ye, Stephen Tong
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3387233?pdf=render

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