Castleman disease (literature review)

Castleman disease (angiofollicular hyperplasia of lymph nodes) – a rare benign lymphoproliferative disease with prolonged asymptomatic course, associated with a wide variety of autoimmune and oncological diseases and the risk of non-Hodgkin’s lymphoma. The rare occurrence of this disease and a varie...

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Main Authors: A. L. Melikyan, E. K. Egorova
Format: Article
Language:Russian
Published: ABV-press 2016-08-01
Series:Онкогематология
Subjects:
Online Access:https://oncohematology.abvpress.ru/ongm/article/view/192
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author A. L. Melikyan
E. K. Egorova
author_facet A. L. Melikyan
E. K. Egorova
author_sort A. L. Melikyan
collection DOAJ
description Castleman disease (angiofollicular hyperplasia of lymph nodes) – a rare benign lymphoproliferative disease with prolonged asymptomatic course, associated with a wide variety of autoimmune and oncological diseases and the risk of non-Hodgkin’s lymphoma. The rare occurrence of this disease and a variety of clinical course did not allow for a complete and consistent research on the etiology and pathogenesis and the standard therapies development. In recent years, the number of patients with Castleman disease in the Russian Federation has increased, which requires its recognition among non-neoplastic and neoplastic lymphadenopathy. The article provides an overview about clinical and histological variants of Castleman’s disease, its pathogenesis concepts, classification and treatment.
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spelling doaj.art-03d08932f0ac4a90b999fdb4261189e22023-03-30T20:15:11ZrusABV-pressОнкогематология1818-83462413-40232016-08-0111282010.17650/1818-8346-2016-11-2-8-20195Castleman disease (literature review)A. L. Melikyan0E. K. Egorova1National Research Center for Hematology, Ministry of Health of Russia; 4 Novyy Zykovskiy Proezd, Moscow, 125167, RussiaNational Research Center for Hematology, Ministry of Health of Russia; 4 Novyy Zykovskiy Proezd, Moscow, 125167, RussiaCastleman disease (angiofollicular hyperplasia of lymph nodes) – a rare benign lymphoproliferative disease with prolonged asymptomatic course, associated with a wide variety of autoimmune and oncological diseases and the risk of non-Hodgkin’s lymphoma. The rare occurrence of this disease and a variety of clinical course did not allow for a complete and consistent research on the etiology and pathogenesis and the standard therapies development. In recent years, the number of patients with Castleman disease in the Russian Federation has increased, which requires its recognition among non-neoplastic and neoplastic lymphadenopathy. The article provides an overview about clinical and histological variants of Castleman’s disease, its pathogenesis concepts, classification and treatment.https://oncohematology.abvpress.ru/ongm/article/view/192castleman diseaseinterleukin-6human herpesvirus type 8
spellingShingle A. L. Melikyan
E. K. Egorova
Castleman disease (literature review)
Онкогематология
castleman disease
interleukin-6
human herpesvirus type 8
title Castleman disease (literature review)
title_full Castleman disease (literature review)
title_fullStr Castleman disease (literature review)
title_full_unstemmed Castleman disease (literature review)
title_short Castleman disease (literature review)
title_sort castleman disease literature review
topic castleman disease
interleukin-6
human herpesvirus type 8
url https://oncohematology.abvpress.ru/ongm/article/view/192
work_keys_str_mv AT almelikyan castlemandiseaseliteraturereview
AT ekegorova castlemandiseaseliteraturereview