Ciliated Hepatic Foregut Cyst: Definitive Diagnosis Is Critical to the Optimal Treatment Pathway

Background. Ciliated hepatic foregut cyst (CHFC) is a rare, benign cyst of the liver, derived from the embryonic foregut epithelium. Although CHFCs are typically asymptomatic, some present with nonspecific abdominal symptoms. Imaging modalities alone are insufficient for diagnosis, with intrahepatic...

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Main Authors: Tatsuhiro Kato, Christine M. G. Schammel, Hubert Fenton, Steven D. Trocha, A. Michael Devane
Format: Article
Language:English
Published: Hindawi Limited 2023-01-01
Series:Case Reports in Hepatology
Online Access:http://dx.doi.org/10.1155/2023/6637890
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author Tatsuhiro Kato
Christine M. G. Schammel
Hubert Fenton
Steven D. Trocha
A. Michael Devane
author_facet Tatsuhiro Kato
Christine M. G. Schammel
Hubert Fenton
Steven D. Trocha
A. Michael Devane
author_sort Tatsuhiro Kato
collection DOAJ
description Background. Ciliated hepatic foregut cyst (CHFC) is a rare, benign cyst of the liver, derived from the embryonic foregut epithelium. Although CHFCs are typically asymptomatic, some present with nonspecific abdominal symptoms. Imaging modalities alone are insufficient for diagnosis, with intrahepatic cholangiocarcinoma included in the differential due to nonspecific imaging features; definitive diagnosis relies on histologic confirmation. These lesions are often benign; however, larger lesions can have malignant transformation into squamous cell carcinoma (SCC), which carries a poor prognosis, thus making a definitive diagnosis, no matter what size, essential. Here, we present a case of CHFC as well as a comprehensive literature review. Given these data, we propose an algorithm for definitive diagnosis.
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spelling doaj.art-03d4cacb76d24e6ea2f0c0b62796b1662023-07-27T00:00:01ZengHindawi LimitedCase Reports in Hepatology2090-65952023-01-01202310.1155/2023/6637890Ciliated Hepatic Foregut Cyst: Definitive Diagnosis Is Critical to the Optimal Treatment PathwayTatsuhiro Kato0Christine M. G. Schammel1Hubert Fenton2Steven D. Trocha3A. Michael Devane4University of South Carolina School of Medicine GreenvilleUniversity of South Carolina School of Medicine GreenvillePathology AssociatesDepartment of SurgeryUniversity of South Carolina School of Medicine GreenvilleBackground. Ciliated hepatic foregut cyst (CHFC) is a rare, benign cyst of the liver, derived from the embryonic foregut epithelium. Although CHFCs are typically asymptomatic, some present with nonspecific abdominal symptoms. Imaging modalities alone are insufficient for diagnosis, with intrahepatic cholangiocarcinoma included in the differential due to nonspecific imaging features; definitive diagnosis relies on histologic confirmation. These lesions are often benign; however, larger lesions can have malignant transformation into squamous cell carcinoma (SCC), which carries a poor prognosis, thus making a definitive diagnosis, no matter what size, essential. Here, we present a case of CHFC as well as a comprehensive literature review. Given these data, we propose an algorithm for definitive diagnosis.http://dx.doi.org/10.1155/2023/6637890
spellingShingle Tatsuhiro Kato
Christine M. G. Schammel
Hubert Fenton
Steven D. Trocha
A. Michael Devane
Ciliated Hepatic Foregut Cyst: Definitive Diagnosis Is Critical to the Optimal Treatment Pathway
Case Reports in Hepatology
title Ciliated Hepatic Foregut Cyst: Definitive Diagnosis Is Critical to the Optimal Treatment Pathway
title_full Ciliated Hepatic Foregut Cyst: Definitive Diagnosis Is Critical to the Optimal Treatment Pathway
title_fullStr Ciliated Hepatic Foregut Cyst: Definitive Diagnosis Is Critical to the Optimal Treatment Pathway
title_full_unstemmed Ciliated Hepatic Foregut Cyst: Definitive Diagnosis Is Critical to the Optimal Treatment Pathway
title_short Ciliated Hepatic Foregut Cyst: Definitive Diagnosis Is Critical to the Optimal Treatment Pathway
title_sort ciliated hepatic foregut cyst definitive diagnosis is critical to the optimal treatment pathway
url http://dx.doi.org/10.1155/2023/6637890
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